HGS (gene)
Encyclopedia
Hepatocyte growth factor-regulated tyrosine kinase substrate is an enzyme
that in humans is encoded by the HGS gene
.
with TSG101
, STAM2
, Merlin
, DLG4
, IL2RB
, EPS15
, CLTC
and Signal transducing adaptor molecule.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the HGS gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
HGS (gene) has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with TSG101
TSG101
Tumor susceptibility gene 101, also known as TSG101, is a human gene that encodes for a cellular protein of the same name.-HIV:TSG101 seems to play an important role in the pathogenesis of HIV...
, STAM2
STAM2
Signal transducing adapter molecule 2 is a protein that in humans is encoded by the STAM2 gene.-Interactions:STAM2 has been shown to interact with HGS, Janus kinase 1 and USP8.-Further reading:...
, Merlin
Merlin (protein)
Merlin is a cytoskeletal protein. In humans, it is a tumor suppressor protein involved in Neurofibromatosis type II. Sequence data reveal its similarity to the ERM protein family....
, DLG4
DLG4
PSD-95 also known as SAP-90 is a protein that in humans is encoded by the DLG4 gene....
, IL2RB
IL2RB
Interleukin-2 receptor subunit beta is a protein that in humans is encoded by the IL2RB gene.-Interactions:IL2RB has been shown to interact with HGS, Janus kinase 1, CISH and SHC1.-Further reading:...
, EPS15
EPS15
Epidermal growth factor receptor substrate 15 is a protein that in humans is encoded by the EPS15 gene.-Interactions:EPS15 has been shown to interact with REPS2, HGS, EPN1, CRK and HRB.-Further reading:...
, CLTC
CLTC
Clathrin heavy chain 1 is a protein that in humans is encoded by the CLTC gene.-Interactions:CLTC has been shown to interact with PICALM and HGS.-Further reading:...
and Signal transducing adaptor molecule.