Growth attenuation
Encyclopedia
Growth attenuation is an elective medical treatment which involves administering estrogen
Estrogen
Estrogens , oestrogens , or œstrogens, are a group of compounds named for their importance in the estrous cycle of humans and other animals. They are the primary female sex hormones. Natural estrogens are steroid hormones, while some synthetic ones are non-steroidal...

 to cause closure of the epiphyses
Epiphysis
The epiphysis is the rounded end of a long bone, at its joint with adjacent bone. Between the epiphysis and diaphysis lies the metaphysis, including the epiphyseal plate...

 of the bone
Bone
Bones are rigid organs that constitute part of the endoskeleton of vertebrates. They support, and protect the various organs of the body, produce red and white blood cells and store minerals. Bone tissue is a type of dense connective tissue...

s (Epiphyseal plate
Epiphyseal plate
The epiphyseal plate is a hyaline cartilage plate in the metaphysis at each end of a long bone...

s), resulting in a reduced adult height. Since the 1960s this treatment has been performed primarily on children growing toward an adult height considered unacceptably excessive by their parents and doctors. The cultural consensus of what is considered an excessive height justifying treatment has differed in Europe and North America and has risen over the last 4 decades.

Most of the children treated have been girls, with larger numbers treated in Europe than in North America. The height considered unacceptable by parents and doctors has become substantially taller over the last few decades. Very few boys have ever been treated for excessive tallness in North America, but this also has been done more often in Europe.

More recently, growth attenuation treatment has been in the news as part of the controversial Ashley Treatment
Ashley Treatment
The Ashley Treatment refers to a controversial set of medical procedures undergone by a Seattle child, "Ashley X". Ashley, born in 1997, has severe developmental disabilities due to static encephalopathy of unknown etiology; she is, and will remain, at an infant level mentally and physically...

administered to a developmentally disabled girl.
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