Glia maturation factor is a nerve growth factor

Nerve growth factor

Nerve growth factor is a small secreted protein that is important for the growth, maintenance, and survival of certain target neurons . It also functions as a signaling molecule. It is perhaps the prototypical growth factor, in that it is one of the first to be described...

 implicated in nervous system development, angiogenesis and immune function.

The structures of mouse glia maturation factors beta and gamma, solved by both crystallography and NMR, reveal similarities and critical differences with ADF-H (actin depolymerization factor homology) domains

ADF-H domain

In molecular biology, ADF-H domain is an approximately 150 amino acid motif that is present in three phylogenetically distinct classes of eukaryotic actin-binding proteins....

and suggest new means of experimentally addressing the function of this protein family.

See also