Ginkgolide
Encyclopedia
Ginkgolides are biologically active terpenic
lactone
s present in Ginkgo biloba. They are diterpenoids with 20-carbon skeletons, which are biosynthesized from geranylgeranyl pyrophosphate
.
Gingkolide B may be effective as preventive treatment in reducing migraine attack frequency.
Terpenoid
The terpenoids , sometimes called isoprenoids, are a large and diverse class of naturally occurring organic chemicals similar to terpenes, derived from five-carbon isoprene units assembled and modified in thousands of ways. Most are multicyclic structures that differ from one another not only in...
lactone
Lactone
In chemistry, a lactone is a cyclic ester which can be seen as the condensation product of an alcohol group -OH and a carboxylic acid group -COOH in the same molecule...
s present in Ginkgo biloba. They are diterpenoids with 20-carbon skeletons, which are biosynthesized from geranylgeranyl pyrophosphate
Geranylgeranyl pyrophosphate
Geranylgeranyl pyrophosphate is an intermediate in the HMG-CoA reductase pathway used by organisms in the biosynthesis of terpenes and terpenoids. In plants it is also the precursor to carotenoids, gibberellins, tocopherols, and chlorophylls....
.
| |R1 | R2 | R3 | |
| A | OH | H | H |
| B | OH | OH | H |
| C | OH | OH | OH |
| J | OH | H | OH |
| M | H | OH | OH |
Gingkolide B may be effective as preventive treatment in reducing migraine attack frequency.