George P. Chrousos
Encyclopedia
George P. Chrousos is professor and chairman of the Department of Pediatrics at the Athens University Medical School. He was previously Senior Investigator, Director of the Pediatric Endocrinology
Section and Training Program, and Chief of the Pediatric and Reproductive Endocrinology Branch of the National Institute of Child Health and Human Development
(NICHD), National Institutes of Health
(NIH). He is also Clinical Professor of Pediatrics, Physiology and Biophysics at Georgetown University Medical School and Distinguished Visiting Scientist, NICHD, NIH. Dr. Chrousos was the first General Director of the Foundation of Biomedical Research of the Academy of Athens (2001–2002)http://www.bioacademy.gr//index.php. He holds the UNESCO Chair on Adolescent Health Care and the John Kluge Chair in Technology and Society, Library of Congress, Washington, D.C. http://www.loc.gov/today/pr/2011/11-050.html.
Dr. Chrousos is among the 250 most prominent clinical investigators in the world. He has authored more than 1100 scientific publications, has edited 26 books and his work has been cited over 57,000 times. According to the ISI he is the highest cited Clinical Pediatrician and Endocrinologist in the world.
, Greece
, attended the University of Athens Medical School and finished as the valedictorian of his class in 1975. He completed his doctorate thesis at the University of Athens, followed by a residency in Pediatrics at New York University Medical School, New York, NY, and a fellowship in Endocrinology, Metabolism and Diabetes at the Clinical Center of the National Institutes of Health, Bethesda, Maryland. He is Board Certified in Pediatrics/ Endocrinology, Metabolism and Diabetes. He has held the positions at NIH of directorship of the ACGME-accredited Affiliate NIH/Georgetown University Pediatric Endocrinology Training Program, Chief of the National Institute of Child Health and Human Development, NIH, Developmental Endocrinology Branch, Pediatric Endocrinology Section, and finally Chief of the National Institute of Child Health and Human Development, Pediatric and Reproductive Endocrinology Branch. Dr. Chrousos went rapidly through the academic hierarchy steps from Assistant Professor to Full Professor of Pediatrics at Georgetown University, which he still holds, in addition to his professorship at Athens.
Endocrinology
Endocrinology is a branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions called hormones, the integration of developmental events such as proliferation, growth, and differentiation and the coordination of...
Section and Training Program, and Chief of the Pediatric and Reproductive Endocrinology Branch of the National Institute of Child Health and Human Development
National Institute of Child Health and Human Development
The Eunice Kennedy Shriver National Institute of Child Health and Human Development , created by Congress in 1962, supports and conducts research on topics related to the health of children, adults, families, and populations...
(NICHD), National Institutes of Health
National Institutes of Health
The National Institutes of Health are an agency of the United States Department of Health and Human Services and are the primary agency of the United States government responsible for biomedical and health-related research. Its science and engineering counterpart is the National Science Foundation...
(NIH). He is also Clinical Professor of Pediatrics, Physiology and Biophysics at Georgetown University Medical School and Distinguished Visiting Scientist, NICHD, NIH. Dr. Chrousos was the first General Director of the Foundation of Biomedical Research of the Academy of Athens (2001–2002)http://www.bioacademy.gr//index.php. He holds the UNESCO Chair on Adolescent Health Care and the John Kluge Chair in Technology and Society, Library of Congress, Washington, D.C. http://www.loc.gov/today/pr/2011/11-050.html.
Dr. Chrousos is among the 250 most prominent clinical investigators in the world. He has authored more than 1100 scientific publications, has edited 26 books and his work has been cited over 57,000 times. According to the ISI he is the highest cited Clinical Pediatrician and Endocrinologist in the world.
Biography
Chrousos was born in PatrasPatras
Patras , ) is Greece's third largest urban area and the regional capital of West Greece, located in northern Peloponnese, 215 kilometers west of Athens...
, Greece
Greece
Greece , officially the Hellenic Republic , and historically Hellas or the Republic of Greece in English, is a country in southeastern Europe....
, attended the University of Athens Medical School and finished as the valedictorian of his class in 1975. He completed his doctorate thesis at the University of Athens, followed by a residency in Pediatrics at New York University Medical School, New York, NY, and a fellowship in Endocrinology, Metabolism and Diabetes at the Clinical Center of the National Institutes of Health, Bethesda, Maryland. He is Board Certified in Pediatrics/ Endocrinology, Metabolism and Diabetes. He has held the positions at NIH of directorship of the ACGME-accredited Affiliate NIH/Georgetown University Pediatric Endocrinology Training Program, Chief of the National Institute of Child Health and Human Development, NIH, Developmental Endocrinology Branch, Pediatric Endocrinology Section, and finally Chief of the National Institute of Child Health and Human Development, Pediatric and Reproductive Endocrinology Branch. Dr. Chrousos went rapidly through the academic hierarchy steps from Assistant Professor to Full Professor of Pediatrics at Georgetown University, which he still holds, in addition to his professorship at Athens.
Research
Chrousos has focused his research on the hypothalamic-pituitary-adrenal (HPA) axis and has extensively studied the neuroendocrine alterations associated with mood disorders, sleep, pain perception, and immune function. In particular, he has worked on the glucocorticoid signaling system diseases of the HPA axis, such as Cushing’s syndrome, Addison’s disease, and congenital adrenal hyperplasia, and the physiologic and molecular mechanisms of stress. Early in his career, he described in the Journal of Clinical Investigation the Glucocorticoid Resistance Syndrome, a rare genetic disease of the glucocorticoid receptor that causes hypertension and hyperandrogenism in children and adults http://www.ncbi.nlm.nih.gov/pubmed/20649902. Subsequently, he has contributed the majority of the international original publications on this syndrome, which has served as a model of the study of the physiologic functions of these key steroid hormones that regulate the homeostasis of the organism.Publications
He has an outstanding record of over 1100 scientific papers, edited 26 books, including 2 popular electronic volumes and 2 encyclopedias, and his work has been cited over 57,000 times throughout the scientific literature. He is one of the most cited physician scientists in the world (Institute of Scientific Information, ISI highly cited) both in the fields of Clinical Medicine and Biology and Biochemistry. Dr. Chrousos’s published work has an h index of over 120. He has published his work in journals of the highest caliber, such as the New England Journal of Medicine, the Journal of Clinical Investigation, the Annals of Internal Medicine, PNAS, Science, Nature, etc.Teaching
He has helped to develop the careers of over 60 young physicians and scientists, many of whom are now professors and chairpersons in Europe, the United States, Australia and Latin America, and directed several training programs for physicians for many years. He taught at the University of Ioannina Medical School, Greece for 10 years (1980–1990). He has had a number of visiting professorships and given prestigious and named lectures throughout the world.Honors
- 2011 The Bodossaki Aristeion Prize, Bodossaki Foundation, Athens, Greece ( http://www.bodossaki.gr/Default.aspx?lang=2)
- 2011 John Kluge Chair in Technology and Society http://www.loc.gov/loc/kluge/fellowships/chairs.html, Library of Congress, Washington, D.C.
- 2010 Member, Academia Europaea http://www.acadeuro.org/, London, UK
- 2010 Foreign Associate Member, Institute of Medicine http://www.iom.edu/, The National Academies, Washington, D.C.
- 2010 Philip S. Hench Memorial Lecture, American College of Rheumatology http://www.rheumatology.org/, Atlanta, GA.
- 2010 UNESCO http://www.unesco.org/new/en/unesco/ Chair on Adolescent Health Care, University of Athens, Athens, Greece
- 2009 Mortimer B. Lipsett Memorial Lecture, NIH.
- 2008 Geoffrey Harris Award of the European Society of Endocrinology European Society of EndocrinologyEuropean Society of EndocrinologyThe European Society of Endocrinology is a scientific society to promote for the public benefit research, education and clinical practice in endocrinology by the organisation of conferences, training courses and publications, by raising public awareness, liaison with national and international...
- Doctor Honoris Causa from the Universities of Liege, Belgium and Ancona, Italy
- President of the European Society of Clinical Investigation http://www.esci.eu.com/
- Honorary Fellow (FRCP), Royal College of Physicians, London, UK Royal College of PhysiciansRoyal College of PhysiciansThe Royal College of Physicians of London was founded in 1518 as the College of Physicians by royal charter of King Henry VIII in 1518 - the first medical institution in England to receive a royal charter...
- Master of the American College of Endocrinology (MACE) http://www.aace.com/college/
- Master of the American College of Physicians (MACP) American College of PhysiciansAmerican College of PhysiciansThe American College of Physicians is a national organization of doctors of internal medicine —physicians who specialize in the prevention, detection, and treatment of illnesses in adults. With 130,000 members, ACP is the largest medical-specialty organization and second-largest physician group in...
- 2004 Lifetime Achievement Award of the International Society of Psychoneuroendocrinology http://www.ispne.org/
- 2002 Sir Edward Sharpey-Schafer Medal of the British Endocrine Societies http://www.endocrinology.org/
- 1999 Novera Herbert Spector Award of the International Society of Neuroimmunomodulation http://www.isnim.org
- 1997 Hans Selye Award http://www.stresscanada.org/
- 1997 Clinical Investigator Award, American Endocrine Society The Endocrine SocietyThe Endocrine SocietyThe Endocrine Society is a professional, international medical organization in the field of endocrinology and metabolism, founded in 1916 as The Association for the Study of Internal Secretions. The official name of the organization was changed to The Endocrine Society on January 1, 1952. It is a...
- 1987 Richard Weitzman Award, American Endocrine Society
Selected papers
- Chrousos, G.P., Gold, P.W. (1992). The Concepts of Stress and Stress System Disorders: Overview of Physical and Behavioral Homeostasis. JAMA 267:1244-1252. Journal of the American Medical Association http://apps.isiknowledge.com/full_record.do?product=WOS&search_mode=CitationReport&qid=3&SID=1F6oK7N7efK7h8pPM1a&page=1&doc=1
- Chrousos, G.P. (1995). Seminars in Medicine of the Beth-Israel Hospital, Boston - The Hypothalamic-Pituitary-Adrenal Axis and Immune-Mediated Inflammation. New England Journal Of Medicine 332:20 1351-1362. http://apps.isiknowledge.com/full_record.do?product=WOS&search_mode=CitationReport&qid=3&SID=1F6oK7N7efK7h8pPM1a&page=1&doc=2
- Gold, P.W., Loriaux, D.L., Roy, A., Kling, M.A., Calabrese, J.R., Kellner, C.H., Nieman, L.K., Post, R.M., Pickar, D., Galluci, W., Avgerinos, P., Paul, S., Oldfield, E.H., Cutler, G.B., Chrousos, G.P. (1986) Responses To Corticotropin-Releasing Hormone in the Hypercortisolism of Depression and Cushings-Disease - Pathophysiologic and Diagnostic Implications. New England Journal of Medicine 314:21 1329-1335 http://apps.isiknowledge.com/full_record.do?product=WOS&search_mode=CitationReport&qid=3&SID=1F6oK7N7efK7h8pPM1a&page=1&doc=4
- Papanicolaou, D.A., Wilder, R.L., Manolagas, S.C., Chrousos, G.P. (1998) The Pathophysiologic Roles of Interleukin-6 in Humans. Ann. Intern. Med. 128:127-137. http://apps.isiknowledge.com/full_record.do?product=WOS&search_mode=CitationReport&qid=3&SID=1F6oK7N7efK7h8pPM1a&page=1&doc=7
- Gold, P.W., Goodwin, F., Chrousos, G.P. (1988) Clinical and Biochemical Manifestations of Depression: Relationship to the Neurobiology of Stress. (Part I and Part 2) N. Engl. J. Med. 319: 348-353 and 319: 413-420. http://apps.isiknowledge.com/full_record.do?product=WOS&search_mode=CitationReport&qid=3&SID=1F6oK7N7efK7h8pPM1a&page=1&doc=8
- Supplement: Selected Original and Review Papers