Gamma-amino-beta-hydroxybutyric acid
Encyclopedia
gamma-Amino-beta-hydroxybutyric acid (GABOB), also known as gamibetal or buxamin, is a derivative of the neurotransmitter GABA
. It is found naturally in the human body but it is not known whether it has an important physiological role at normal concentrations.
GABOB has anticonvulsant
properties, but is of relatively low potency when used by itself, and is more useful as an adjutant treatment used alongside another anticonvulsant drug. It has two stereoisomers, with the (3S) isomer d-GABOB being around twice as potent an anticonvulsant as the (3R) isomer l-GABOB.
Other studies have suggested it may produce improved learning and memory function, probably through a cholinergic
mechanism, as well as boosting growth hormone
release. However its effectiveness for these purposes has not been well established and it is not widely used in medicine, although it is sold as a dietary supplement
.
Gabâ
Gabâ or gabaa, for the people in many parts of the Philippines), is the concept of a non-human and non-divine, imminent retribution. A sort of negative karma, it is generally seen as an evil effect on a person because of their wrongdoings or transgressions...
. It is found naturally in the human body but it is not known whether it has an important physiological role at normal concentrations.
GABOB has anticonvulsant
Anticonvulsant
The anticonvulsants are a diverse group of pharmaceuticals used in the treatment of epileptic seizures. Anticonvulsants are also increasingly being used in the treatment of bipolar disorder, since many seem to act as mood stabilizers, and in the treatment of neuropathic pain. The goal of an...
properties, but is of relatively low potency when used by itself, and is more useful as an adjutant treatment used alongside another anticonvulsant drug. It has two stereoisomers, with the (3S) isomer d-GABOB being around twice as potent an anticonvulsant as the (3R) isomer l-GABOB.
Other studies have suggested it may produce improved learning and memory function, probably through a cholinergic
Acetylcholine
The chemical compound acetylcholine is a neurotransmitter in both the peripheral nervous system and central nervous system in many organisms including humans...
mechanism, as well as boosting growth hormone
Growth hormone
Growth hormone is a peptide hormone that stimulates growth, cell reproduction and regeneration in humans and other animals. Growth hormone is a 191-amino acid, single-chain polypeptide that is synthesized, stored, and secreted by the somatotroph cells within the lateral wings of the anterior...
release. However its effectiveness for these purposes has not been well established and it is not widely used in medicine, although it is sold as a dietary supplement
Dietary supplement
A dietary supplement, also known as food supplement or nutritional supplement, is a preparation intended to supplement the diet and provide nutrients, such as vitamins, minerals, fiber, fatty acids, or amino acids, that may be missing or may not be consumed in sufficient quantities in a person's diet...
.