Gajendra Pal Singh Raghava - AbsoluteAstronomy.com

Gajendra Pal Singh Raghava is a bio-informatician and head of the Bioinformatics Centre at the Institute of Microbial Technology (IMTECH

Imtech

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Early years and Education

Raghava was born in village Nagla Karan, Buland Shahr (UP), India in 1963. He did his B.Sc./M.Sc. from N.A.S. College, Meerut, UP in 1982. His major subjects were Physics, Chemistry and Mathematics. He did his M.Sc in Physics with specialization in electronics from N.A.S. College, Meerut, UP in 1984. He did his M.Tech from Indian Institute of Technology (I.I.T.), New Delhi in 1986. In 1996 he received a doctorate in bioinformatics from Institute of Microbial Technology and Panjab University, Chandigarh. His thesis was on "Computer Aided Prediction of Protein Conformation from Amino Acid Sequences of Biotechnological Relevance".

Career and Higher Studies

He joined the Institute of Microbial Technology, Chandigarh in 1986 as a computer scientist and developer. He become head of the Bioinformatics Centre in 1994. He is also coordinator of the distributed information centre supported by DBT under the BTISNET programme, where his primary duty is to build and maintain infrastructure required for protein modeling and engineering.

He worked as a postdoctoral fellow at Oxford university as well as at the European Bioinformatics Institute (EBI) at Cambridge for two years (1996–98). During this period he learned and developed a number of web servers for application in computational biology, particularly in protein modelling.

Achievements and Awards

Dr. G. P. S. Raghava has been selected for J.C. Bose National Fellowship for the year 2010, constituted by Department of Science and Technology.
Dr Raghava selected for NASI-Reliance Industries Platinum Jubilee Awards, 2009 in Biological Sciences.
Raghava bags Thomson Reuters Research Excellence ~ India Research Front Awards 2009
Raghava got prestigious Shanti Swarup Bhatnagar Prize for Science and Technology for 2008
Raghava got National Bioscience Award of year 2005-6 for carrier development of Department of Biotechnology (Govt. of India) New Delhi
BBSRC fellowship, funded by UK for postdoctoral studies at Oxford University, UK from 1996 to 1998. During this period I developed a number of web servers in the area of computational biology particularly in Protein Modelling.
Government of Korea offered Visiting Professorship for six months (March 2004 to August 2004) to initiate Bioinformatics activities at Pohang University of Science and Technology (POSTECH).
Invited by University of Arkansas for Medical Sciences (UAMS), Little Rock, USA to establish Bioinformatics (http://bioinformatics.uams.edu/)
Dr Raghava has published more than 90 research papers in reputed journals, developed 7 currated databases and more than 80 web servers, and 30 copyrights.
Raghava was a key figure in the development of the BioSuite software developed by TCS under NMITLI programmee, launched on the 14 July 2004.
His group in collaboration with Biomantra, a private company, developed a software package VaxiPred: Computer aided vaccine design, which was launched by Director General, CSIR Dr R A Mashlekar on 15 December 2004.

Positions

Raghava ranked 54th among world-wide bioinformatics heads and 1st in Indian bioinformatics heads according to site Bioinformatics Lab Registry
He was elected as Fellow of National Academy of Sciences by The National Academy of Sciences, India for his excellent contribution in the field of Bioinformatics.
He was elected Fellow of the Indian Academy of Sciences, Banglore for his excellent contribution in the field of Bioinformatics.
Dr. Raghava is listed as a hot 100 authors by BioMed Central for his contributions
Dr Raghava has H-index 27 and g-index 41 in July 2009 as per Google scholar. H-index is used to measure performance of a researcher.
Associate Editor of BMC Research Notes.
Associate Editor of BMC Bioinformatics.
Member of Editorial Board of Journal of Biomedical Science and Engineering.
Associate Editor of Journal of Applied Sciences.
Member of Editorial Advisory Board of journal Recent Patents on DNA & Gene Sequences
Member of Editorial Advisory Board of journal The Open Bioinformatics Journal

Research interests

He developed a method for calculating concentration of antibodies and antigens from ELISA data, and he a prediction method for protein secondary structure prediction. In 1999 he established his research group at IMTECH with emphasis on protein structure prediction and genome annotation. In 2001, his group also focused on "Computer aided vaccine design" with emphasis on subunit vaccine design. Since 2006, his group is trying to integrate bioinformatics, chemoinformatics, pharmaco-informatics and clinical informatics in order to develop a single plate form for designing drugs in silico.

Web Services and Software

He is an adherent of public domain software

Public domain software

Public domain software is software that has been placed in the public domain, in other words there is absolutely no ownership of the intellectual property that the software represents....

or open source software, and his group both uses and develops free software for academic use. Recently his group have initiated a web portal Computational Resource for Drug Discovery (CRDD)

Computational Resource for Drug Discovery (CRDD)

Computational Resources for Drug Discovery is one of the important silico modules of Open Source for Drug Discovery . The CRDD web portal provides computer resources related to drug discovery on a single platform...

under Open Source Drug Discovery . Services provided from his group can be broadly classified in the following categories.

Computer-aided Protein Structure Prediction

**Table I**
APSSP2	PROCLASS	PSA	RPFOLD	BTEVAL	BetatPred2	BetatPred	CHpredict	AR_NHPred
TBBPred	BetaTurns	BhairPred	OXBench	StruComp	GammaPred	AlphaPred	PepStr	SarPred

Immunoinformatics: Subunit Vaccine design

**Table II**
PROPRED1	nHLApred	MMBpred	Pcleavage	TAPpred	CTLpred	PROPRED
HLADR4pred	MHC2pred	MHC	MHCbench	AbAg	BCEpred	ABCpred
BCIPep	HLApred	MHCBN	HaptenDB	HLA_affi	FDR4	Tmhcpred
CBtope	NPtope

Genome Annotation

**Table III**
FTG	GWBLAST	GWFASTA	EGPred	SVMgene
SRF	MyPattern	GeneBench	FTGPred	CDpred
DNAbinder	Polyapred	Pprint	ECGpred	SGpred
PHDcleav	siRNApred	DesiRm	MARSpred	Iccaars

Functional Annotation of Proteins

**Table IV**
AC2Dgel	NRpred	GPCRpred	GPCRsclass	ESLpred	PSLpred	BTXpred	Mitpred	ESLpred2
SRTpred	Oxypred	VGIchan	HSLpred	DNAsize	GSTpred	Mango	LGEpred	CytoPred
NTXpred	VICMpred	AlgPred	PseaPred	RSL-Pred	AntiBP	COPid	siRNAPred	ISSPred
SubMitPred	CyclinPred	ChemoPred	TBPred	ProPrint	plPred	PseaPred2	ChloroPred	SPred
PFMPred	CancerPred

Chemoinformatics and Pharmacoinformatics

**Table V**
DADPRED	DMKPred	KiDoQ	AntiBP	AntiBP2	TOXIpred

Unclassified webservers and webpages

**Table VI**
Crag	CRIP	HIVbio	BioTherapy	GDPbio	DrugPedia
LibNet	Address	RBpred	Hplot	Mafft	SFEpred
OC Web	Protanal	Strucomp	Sci. Writ	Aasim	BioSuite

Databases

**List of Databases developed**
MHCBN	BCIPEP	HaptenDB	FSGP	PRRDB	HMRbase
AntigenDB	PolysacDB	OXDBase	BIAdb	SFdbase	HIVsir

News from Group

OSCAT2012 : 2nd International conference on open source for computer-aided Translational medicine.

PreMier: Identification of Mannose Interacting Residues Using Local Composition". Plos ONE 6: e24039
TumorHope : A database of tumor homing peptides
ccPDB: Compilation and creation of datasets from protein data bank (PDB)
GenomeABC : A server for Benchmarking of Genome Assemblers.
DESTAMP: Designing of stable antibacterial peptides.
DRONA: Prediction of nucleic acids (DNA RNA) interacting residues in proteins

External links

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