GATA4
Encyclopedia
Transcription factor GATA-4 is a protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...

 that in humans is encoded by the GATA4 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

.

Interactions

GATA4 has been shown to interact
Protein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...

 with NKX2-5
NKX2-5
Homeobox protein Nkx-2.5 is a protein that in humans is encoded by the NKX2-5 gene.-Interactions:NKX2-5 has been shown to interact with GATA4 and TBX5....

, TBX5
TBX5 (gene)
T-box transcription factor TBX5 is a protein that in humans is encoded by the TBX5 gene.-Interactions:TBX5 has been shown to interact with GATA4 and NKX2-5.-External Links:*...

, ZFPM2
ZFPM2
Zinc finger protein ZFPM2 is a protein that in humans is encoded by the ZFPM2 gene.-Interactions:ZFPM2 has been shown to interact with GATA4, GATA1 and CTBP2.-Further reading:...

, Serum response factor
Serum response factor
Serum response factor , also known as SRF, is a transcription factor.It is a member of the MADS box superfamily of transcription factors. This protein binds to the serum response element in the promoter region of target genes...

 and HAND2
HAND2
Heart- and neural crest derivatives-expressed protein 2 is a protein that in humans is encoded by the HAND2 gene.A progesterone-regulated transcription factor regulates stromal-epithelial communication in early pregnancy....

.
HDAC2

External links

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