Francesco II of Lesbos
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Francesco II Gattilusio
Gattilusio
The Gattilusi were a powerful Genoese family who controlled a number of possessions in the northern Aegean from 1355 until the mid 15th century....

, Lord of Lesbos
(born Giacomo Gattilusio or Jacopo c. 1365 - 26 October 1403/1404) was the second ruler of an independent Lesbos from 1384 to his death.

He was the third son of Francesco I of Lesbos
Francesco I of Lesbos
Francesco I Gattilusio, Lord of Lesbos was the first member of the Gattilusio family to rule the Aegean Island of Lesbos.-Freebooter:...

 and Maria Palaiologina. His maternal grandparents were Andronikos III Palaiologos
Andronikos III Palaiologos
Andronikos III Palaiologos, Latinized as Andronicus III Palaeologus was Byzantine emperor from 1328 to 1341, after being rival emperor since 1321. Andronikos III was the son of Michael IX Palaiologos and Rita of Armenia...

 and his second wife Anna of Savoy
Anna of Savoy
Anna of Savoy, born Giovanna, was a Byzantine Empress consort, as the second wife of Andronikos III Palaiologos.-Family:She was a daughter of Amadeus V, Count of Savoy and his second wife Maria of Brabant. Her maternal grandparents were John I, Duke of Brabant and Margaret of Flanders...

.

On 6 August 1384, an earthquake
Earthquake
An earthquake is the result of a sudden release of energy in the Earth's crust that creates seismic waves. The seismicity, seismism or seismic activity of an area refers to the frequency, type and size of earthquakes experienced over a period of time...

 affected Lesbos. Francesco I and his two eldest sons, Andronico and Domenico, were all killed. However the third son Jacopo survived. He succeeded in the rule of Lesbos under the name Francesco II. Francesco II was yet underage and was placed under the regency of his paternal uncle Niccolò of Ainos
Niccolò of Ainos
Niccolò Gattilusio was the first member of the Gattilusio family to rule the city of Aenos .The Gattilusio family came from the Republic of Genoa...

.

Francesco II married a Genoese noblewoman, Valentina Doria
Doria
Doria, originally de Auria , meaning "the sons of Auria", and then de Oria or d'Oria, is the name of an old and extremely wealthy Genoese family who played a major role in the history of the Republic of Genoa and in Italy, from the 12th century to the 16th century.-Origins:According to legend, a...

, daughter of Dorino Doria q. Dorino of Loano and Violante Doria q. Brancaleone II of Sardinia, Lady of Lerma. From a first marriage, Dorino Doria had a son called Pietro Doria, who was none other than the Genoese Admiral who won the battle of Chioggia against the Venetians in 1379 and died a hero in the following year. Francesco and Valentina had six children:
  • Jacopo of Lesbos
    Jacopo of Lesbos
    Jacopo Gattilusio, Lord of Lesbos was the third ruler of an independent Lesbos from 1404 to 1428.He was the eldest son of Francesco II of Lesbos and Valentina Doria. He succeeded to his realm on 26 October 1404.-Marriage:...

    . Ruled from 1403/04 to 1428.
  • Dorino I of Lesbos. Ruled from 1428 to 1455.
  • Palamede, Lord of Ainos
    Palamede, Lord of Ainos
    Palamede Gattilusio was a Lord of Ainos from 1409 to 1455. He was a son of Francesco II of Lesbos, and wife.He married Valentina N and had six children:* Giorgio Gattilusio * Dorino II of Ainos...

    . Ruled Ainos from 1409 to 1455.
  • Irene Gattilusio
    Irene Gattilusio
    Irene Gattilusio, born Eugenia Gattilusio was the wife of John VII Palaiologos, a Byzantine Emperor in 1390.-Family:She was a daughter of Francesco II of Lesbos and Valentina Doria....

    . Married John VII Palaiologos
    John VII Palaiologos
    John VII Palaiologos was Byzantine Emperor for five months in 1390.-Life:...

     and had Andronikos V Palaiologos
    Andronikos V Palaiologos
    Andronikos V Palaiologos was co-emperor of the Byzantine Empire with his father John VII Palaiologos.-Life:...

    .
  • Helena Gattilusio. Married in 1405 Stefan Lazarević
    Stefan Lazarevic
    Stefan Lazarević known also as Stevan the Tall was a Serbian Despot, ruler of the Serbian Despotate between 1389 and 1427. He was the son and heir to Prince Lazar, who died at the Battle of Kosovo against the Turks in 1389, and Princess Milica from the subordinate branch of the Nemanjić dynasty...

    , without any known issue.
  • Caterina Gattilusio. Married Pietro Grimaldi, Baron of Bueil
    Bueil
    Bueil is a commune in the Eure department in Haute-Normandie in northern France.-Population:...

    . They were eleventh generation ancestors of Marquis de Sade
    Marquis de Sade
    Donatien Alphonse François, Marquis de Sade was a French aristocrat, revolutionary politician, philosopher, and writer famous for his libertine sexuality and lifestyle...

    .


He reportedly died in an unusual manner. He was bitten by a scorpion
Scorpion
Scorpions are predatory arthropod animals of the order Scorpiones within the class Arachnida. They have eight legs and are easily recognized by the pair of grasping claws and the narrow, segmented tail, often carried in a characteristic forward curve over the back, ending with a venomous stinger...

. The number of people rushing to his aid resulted in the wooden floor of his room collapsing under their combined weight. The poison did not kill him but the fall did.

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