Fenticonazole is an azole

Azole

An azole is a class of five-membered nitrogen heterocyclic ring compounds containing at least one other non-carbon atom of either nitrogen, sulfur, or oxygen. The parent compounds are aromatic and have two double bonds; there are successively reduced analogs with fewer...

 antifungal drug

Antifungal drug

An antifungal medication is a medication used to treat fungal infections such as athlete's foot, ringworm, candidiasis , serious systemic infections such as cryptococcal meningitis, and others...

, used locally as the nitrate in the treatment of vulvovaginal candidiasis

Candidiasis

Thrush redirects here. For the hoof infection see Thrush .Candidiasis or thrush is a fungal infection of any of the Candida species , of which Candida albicans is the most common...

.

Antimicrobial Action
Fenticonazole is an imidazole antifungal active against a range of organisms including dermatophyte pathogens, Malassezia furfur

Malassezia furfur

Malassezia is a genus of fungi. Malassezia is naturally found on the skin surfaces of many animals, including humans. In occasional opportunistic infections,...

, and Candida albicans

Candida albicans

Candida albicans is a diploid fungus that grows both as yeast and filamentous cells and a causal agent of opportunistic oral and genital infections in humans. Systemic fungal infections including those by C...

.

Uses and Administration
A 200-mg pessary is inserted into the vagina at bedtime for 3 nights or a 600-mg pessary is inserted once only at bedtime. Fenticonazole nitrate is also applied topically as a 2% cream or solution for the treatment of fungal skin infections.

Adverse Effects and Precautions
Burning and itching have been reported after the application of fenticonazole nitrate.

Intravaginal preparations of fenticonazole may damage latex contraceptives and additional contraceptive measures are therefore necessary during local administration.

For a discussion of the caution needed when using azole antifungals during pregnancy, see under Pregnancy in Precautions of Fluconazole, .

Preparations
Single-ingredient Preparations
The symbol ¤ denotes a preparation which is discontinued or no longer actively marketed.

Argentina: Lomexin¤; Austria: Fenizolan¤; Lomexin; Brazil: Fentizol; Lomexin; Czech Republic: Lomexin; France: Lomexin; Terlomexin; Germany: Fenizolan; Lomexin; Greece: Lomexin; Hungary: Gynoxin; Italy: Falvin; Fentiderm¤; Fentigyn¤; Lomexin; Mexico: Lomexin; South Africa: Lomexin; Singapore: Lomexin¤; Spain: Laurimic; Lomexin; Micofulvin¤; Switzerland: Mycodermil; United Kingdom: Lomexin¤; Venezuela: Mycofentin;