Febrifugine
Encyclopedia
Febrifugine is a quinazolinone
alkaloid first isolated from Chinese herb Dichroa febrifuga
, but also found in the garden plant Hydrangea
.
Febrifugine has antimalarial properties and the halogen
ated derivative halofuginone
is used in veterinary medicine as a coccidiostat
.
Quinazolinone
Quinazolinone is a heterocyclic chemical compound. There are two structural isomers, 2-quinazolinone and 4-quinazolinone, with the 4-isomer being the more common.-Derivatives:...
alkaloid first isolated from Chinese herb Dichroa febrifuga
Dichroa febrifuga
Dichroa febrifuga is a flowering plant in the family Hydrangeaceae.-Medicinal uses:It is an important herb in traditional Chinese medicine, where it is considered one of the 50 fundamental herbs.-External links:*...
, but also found in the garden plant Hydrangea
Hydrangea
Hydrangea is a genus of about 70 to 75 species of flowering plants native to southern and eastern Asia and North and South America. By far the greatest species diversity is in eastern Asia, notably China, Japan, and Korea...
.
Febrifugine has antimalarial properties and the halogen
Halogen
The halogens or halogen elements are a series of nonmetal elements from Group 17 IUPAC Style of the periodic table, comprising fluorine , chlorine , bromine , iodine , and astatine...
ated derivative halofuginone
Halofuginone
Halofuginone is a coccidiostat used in veterinary medicine. It is a synthetic halogenated derivative of febrifugine, a natural quinazolinone alkaloid which can be found in the Chinese herb Dichroa febrifuga . Collgard Biopharmaceuticals is developing halofuginone for the treatment of scleroderma...
is used in veterinary medicine as a coccidiostat
Coccidiostat
A coccidiostat is an antiprotozoal agent that acts upon Coccidia parasites.Examples include:* amprolium* arprinocid* artemether* clopidol* decoquinate* diclazuril* dinitolmide* ethopabate* halofuginone* lasalocid* monensin* narasin* nicarbazin...
.