F. Peter Guengerich
Encyclopedia
Dr. F. Peter Guengerich is a professor of biochemistry
and the director of the Center in Molecular Toxicology at Vanderbilt University
, Nashville
, Tennessee
. Dr. Guengerich is the author or co-author of over 500 peer-reviewed scientific articles, and a researcher in toxicology
working on cytochromes P450
, DNA
damage and carcinogenesis
, and drug metabolism
. In 2005 he received the William C. Rose Award
for his research.
Biochemistry
Biochemistry, sometimes called biological chemistry, is the study of chemical processes in living organisms, including, but not limited to, living matter. Biochemistry governs all living organisms and living processes...
and the director of the Center in Molecular Toxicology at Vanderbilt University
Vanderbilt University
Vanderbilt University is a private research university located in Nashville, Tennessee, United States. Founded in 1873, the university is named for shipping and rail magnate "Commodore" Cornelius Vanderbilt, who provided Vanderbilt its initial $1 million endowment despite having never been to the...
, Nashville
Nashville, Tennessee
Nashville is the capital of the U.S. state of Tennessee and the county seat of Davidson County. It is located on the Cumberland River in Davidson County, in the north-central part of the state. The city is a center for the health care, publishing, banking and transportation industries, and is home...
, Tennessee
Tennessee
Tennessee is a U.S. state located in the Southeastern United States. It has a population of 6,346,105, making it the nation's 17th-largest state by population, and covers , making it the 36th-largest by total land area...
. Dr. Guengerich is the author or co-author of over 500 peer-reviewed scientific articles, and a researcher in toxicology
Toxicology
Toxicology is a branch of biology, chemistry, and medicine concerned with the study of the adverse effects of chemicals on living organisms...
working on cytochromes P450
Cytochrome P450 oxidase
The cytochrome P450 superfamily is a large and diverse group of enzymes. The function of most CYP enzymes is to catalyze the oxidation of organic substances. The substrates of CYP enzymes include metabolic intermediates such as lipids and steroidal hormones, as well as xenobiotic substances...
, DNA
DNA
Deoxyribonucleic acid is a nucleic acid that contains the genetic instructions used in the development and functioning of all known living organisms . The DNA segments that carry this genetic information are called genes, but other DNA sequences have structural purposes, or are involved in...
damage and carcinogenesis
Carcinogenesis
Carcinogenesis or oncogenesis is literally the creation of cancer. It is a process by which normal cells are transformed into cancer cells...
, and drug metabolism
Drug metabolism
Drug metabolism is the biochemical modification of pharmaceutical substances by living organisms, usually through specialized enzymatic systems. This is a form of xenobiotic metabolism. Drug metabolism often converts lipophilic chemical compounds into more readily excreted polar products...
. In 2005 he received the William C. Rose Award
William C. Rose Award
The William C. Rose Award given by the American Society for Biochemistry and Molecular Biology recognizes outstanding contributions to biochemical and molecular biological research and a demonstrated commitment to the training of younger scientists, as epitomized by the late American nutritionist...
for his research.