Extra-amniotic administration is a route of administration

Route of administration

A route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body.-Classification:Routes of administration are usually classified by application location...

 to the space between the fetal membranes

Fetal membranes

The fetal membranes, or chorioamniotic membranes, are the amnion and chorion which surround and protect a developing fetus....

 and endometrium

Endometrium

-Function:The endometrium is the innermost glandular layer and functions as a lining for the uterus, preventing adhesions between the opposed walls of the myometrium, thereby maintaining the patency of the uterine cavity. During the menstrual cycle or estrous cycle, the endometrium grows to a...

 inside the uterus

Uterus

The uterus or womb is a major female hormone-responsive reproductive sex organ of most mammals including humans. One end, the cervix, opens into the vagina, while the other is connected to one or both fallopian tubes, depending on the species...

 of a pregnant woman.

It can be used to administer drugs affecting uterus

Uterus

The uterus or womb is a major female hormone-responsive reproductive sex organ of most mammals including humans. One end, the cervix, opens into the vagina, while the other is connected to one or both fallopian tubes, depending on the species...

 motility, such as oxytocin

Oxytocin

Oxytocin is a mammalian hormone that acts primarily as a neuromodulator in the brain.Oxytocin is best known for its roles in sexual reproduction, in particular during and after childbirth...

 and prostaglandins, e.g. in labor induction or medical abortion

Medical abortion

A medical abortion is a type of non-surgical abortion in which abortifacient pharmaceutical drugs are used to induce abortion. An oral preparation for medical abortion is commonly referred to as an abortion pill....

.

Method

It can be performed using a catheter with a balloon that is inserted under direct vision through the cervix. The balloon is inflated with 30 ml of sterile water, allowing medication to be injected through the catheter into the extra-amniotic space.