Ethyl chloroformate
Encyclopedia
Ethyl chloroformate is the ethyl
ester
of chloroformic acid
. It is a reagent
used in organic synthesis
for the introduction of the ethyl carbamate
protecting group
and for the formation of carboxylic anhydride
s.
Ethyl group
In chemistry, an ethyl group is an alkyl substituent derived from ethane . It has the formula -C2H5 and is very often abbreviated -Et.Ethylation is the formation of a compound by introduction of the ethyl functional group, C2H5....
ester
Ester
Esters are chemical compounds derived by reacting an oxoacid with a hydroxyl compound such as an alcohol or phenol. Esters are usually derived from an inorganic acid or organic acid in which at least one -OH group is replaced by an -O-alkyl group, and most commonly from carboxylic acids and...
of chloroformic acid
Chloroformic acid
Chloroformic acid is an unstable chemical compound with the formula ClCO2H. It is the single acyl-halide derivative of carbonic acid . Chloroformic acid is also structurally related to formic acid, which has a hydrogen instead of the chlorine...
. It is a reagent
Reagent
A reagent is a "substance or compound that is added to a system in order to bring about a chemical reaction, or added to see if a reaction occurs." Although the terms reactant and reagent are often used interchangeably, a reactant is less specifically a "substance that is consumed in the course of...
used in organic synthesis
Organic synthesis
Organic synthesis is a special branch of chemical synthesis and is concerned with the construction of organic compounds via organic reactions. Organic molecules can often contain a higher level of complexity compared to purely inorganic compounds, so the synthesis of organic compounds has...
for the introduction of the ethyl carbamate
Ethyl carbamate
Ethyl carbamate is a chemical compound with the molecular formula C3H7NO2 first prepared in the nineteenth century. Structurally, it is an ester of carbamic acid...
protecting group
Protecting group
A protecting group or protective group is introduced into a molecule by chemical modification of a functional group in order to obtain chemoselectivity in a subsequent chemical reaction...
and for the formation of carboxylic anhydride
Carboxylic anhydride
"Anhydride" redirects here. For inorganic acid anhydrides see acidic oxide.An acid anhydride is an organic compound that has two acyl groups bound to the same oxygen atom. Most commonly, the acyl groups are derived from the same carboxylic acid, the formula of the anhydride being 2O...
s.