Ethanolamine-O-sulfate
Encyclopedia
Ethanolamine-O-sulfate (EOS) is an ester
of sulfuric acid
and ethanolamine
. EOS is a GABA transaminase inhibitor
which prevents the metabolism of GABA
. It is used as a biochemical tool in studies involving GABA.
EOS is also a diuretic
and an anticonvulsant
.
Ester
Esters are chemical compounds derived by reacting an oxoacid with a hydroxyl compound such as an alcohol or phenol. Esters are usually derived from an inorganic acid or organic acid in which at least one -OH group is replaced by an -O-alkyl group, and most commonly from carboxylic acids and...
of sulfuric acid
Sulfuric acid
Sulfuric acid is a strong mineral acid with the molecular formula . Its historical name is oil of vitriol. Pure sulfuric acid is a highly corrosive, colorless, viscous liquid. The salts of sulfuric acid are called sulfates...
and ethanolamine
Ethanolamine
Ethanolamine, also called 2-aminoethanol or monoethanolamine , is an organic chemical compound that is both a primary amine and a primary alcohol . Like other amines, monoethanolamine acts as a weak base...
. EOS is a GABA transaminase inhibitor
GABA transaminase inhibitor
A GABA transaminase inhibitor is an enzyme inhibitor that acts upon GABA transaminase.Examples include vigabatrin and ethanolamine-O-sulfate .Certain members of this class are used as anticonvulsants....
which prevents the metabolism of GABA
Gabâ
Gabâ or gabaa, for the people in many parts of the Philippines), is the concept of a non-human and non-divine, imminent retribution. A sort of negative karma, it is generally seen as an evil effect on a person because of their wrongdoings or transgressions...
. It is used as a biochemical tool in studies involving GABA.
EOS is also a diuretic
Diuretic
A diuretic provides a means of forced diuresis which elevates the rate of urination. There are several categories of diuretics. All diuretics increase the excretion of water from bodies, although each class does so in a distinct way.- Medical uses :...
and an anticonvulsant
Anticonvulsant
The anticonvulsants are a diverse group of pharmaceuticals used in the treatment of epileptic seizures. Anticonvulsants are also increasingly being used in the treatment of bipolar disorder, since many seem to act as mood stabilizers, and in the treatment of neuropathic pain. The goal of an...
.