Esen Buqa II was Khan of Moghulistan

Moghulistan

Moghulistan or Mughalistan is a historical geographic unit in Central Asia that included parts of modern-day Kazakhstan, Kyrgyzstan, and the Chinese Autonomous Region of Xinjiang...

 from 1429 until his death. He was the younger son of Uwais Khan

Uwais Khan

Awais Khan:Awais Khan ibn Sher 'Ali was one of the chagatai khans of Mughalistan from 1418-1421 and again from 1425-1429...

.

When Uwais Khan was killed in 1428 the Moghuls were thrown into a state of confusion. Some of them supported Esen Buqa, while others supported his older brother, Yunus Khan

Yunus Khan

Yunus Khan , was Khan of Moghulistan from 1462 until his death. He is identified by many historians with Ḥājjī `Ali , of the contemporary Chinese records.- Background and Family :...

. The party of Yunus Khan, however, found themselves a minority and fled to the Timurid Ulugh Beg

Ulugh Beg

Ulugh Bek was a Timurid ruler as well as an astronomer, mathematician and sultan. His commonly-known name is not truly a personal name, but rather a moniker, which can be loosely translated as "Great Ruler" or "Patriarch Ruler" and was the Turkic equivalent of Timur's Perso-Arabic title Amīr-e...

.

With Yunus Khan's departure, Esen Buqa was the uncontested khan. The first few years of his reign went by smoothly; all of the Moghuls were loyal to him, while the town of Kashgar

Kashgar

Kashgar or Kashi is an oasis city with approximately 350,000 residents in the western part of the Xinjiang Uyghur Autonomous Region of the People's Republic of China. Kashgar is the administrative centre of Kashgar Prefecture which has an area of 162,000 km² and a population of approximately...

, which had been captured by the Timurids after Uwais Khan had died, was retaken in 1435. However, the Amirs

Emir

Emir , meaning "commander", "general", or "prince"; also transliterated as Amir, Aamir or Ameer) is a title of high office, used throughout the Muslim world...

 thought little of Esen Buqa, who had ascended the throne while still a child. They began to resent his authority and the country fell into a state of disorder. The khan moved to Aksu and after some time managed to regain the loyalty of the amirs. As result he gave his daughter Daulat Nigar Khanim in marriage to Muhammad Haidar Mirza, son of Dughlat Amir of Kashgar Sayyid Ali.

Soon after he had regained control of Moghulistan, Esen Buqa began to conduct raids into the territory of Timurids of Transoxiana

Transoxiana

Transoxiana is the ancient name used for the portion of Central Asia corresponding approximately with modern-day Uzbekistan, Tajikistan, southern Kyrgystan and southwest Kazakhstan. Geographically, it is the region between the Amu Darya and Syr Darya rivers...

. In 1451 he attacked Tashkent

Tashkent

Tashkent is the capital of Uzbekistan and of the Tashkent Province. The officially registered population of the city in 2008 was about 2.2 million. Unofficial sources estimate the actual population may be as much as 4.45 million.-Early Islamic History:...

, and a second expedition was undertaken soon afterwards. He also besieged and temporarily gained control over Andijan

Andijan

Andijan or Andizhan is the fourth-largest city in Uzbekistan, and the capital of the Andijan Province. It is located in the east of the country, at , in the Fergana Valley, near the border with Kyrgyzstan on the Andijan-Say River...

. The Timurid Abu Sa'id

Abu Sa'id (Timurid dynasty)

Abū Saʿīd b. Muḥammad b. Mīrānshāh b. Timūr , was a Timurid Empire ruler in what is today parts of Kazakhstan, Uzbekistan, Iran and Afghanistan and member of the Timurid dynasty....

 had the military strength to defeat the Moghuls in Transoxiana, but could not pursue them in Moghulistan.

Frustrated at the continuing Moghul raids, Abu Sa'id sent for Yunus Khan, then in Iraq

Iraq

Iraq ; officially the Republic of Iraq is a country in Western Asia spanning most of the northwestern end of the Zagros mountain range, the eastern part of the Syrian Desert and the northern part of the Arabian Desert....

. He equipped Yunus Khan with an army and sent him to take over Moghulistan. He gained the support of several amirs and approached Kashgar. Esen Buqa caught him a few miles from the town and in the ensuing battle proved victorious, forcing his brother to flee back to Abu Sa'id. A short time later Esen Buqa again had to deal with Yunus Khan, who once again gained the support of the amirs when he entered Moghulistan, but was unable to make any real headway against his brother.

Esen Buqa died of natural causes in 1462, after a khanship of thirty-three years. His death caused a split amongst the Moghuls; in the west Yunus Khan gained power, while in the east Esen Buqa's son Dost Muhammad

Dost Muhammad (Moghul Khan)

Dost Muhammad Khan was Khan of eastern Moghulistan from 1462 until his death. He was the son of Esen Buqa II.When Esen Buqa died in 1462, the Dughlat amirs were divided over whether they should follow his son Dost Muhammad, who was then seventeen, or his brother Yunus Khan...

 became khan.

Esen Buqa is also known for giving refuge to two brothers, Jani Beg and Karai, against the Uzbeks

Uzbeks

The Uzbeks are a Turkic ethnic group in Central Asia. They comprise the majority population of Uzbekistan, and large populations can also be found in Afghanistan, Tajikstan, Kyrgyzstan, Turkmenistan, Kazakhstan, Russia, Pakistan, Mongolia and the Xinjiang Uyghur Autonomous Region of China...

. The friendship between the khan and these two brothers, would eventually found the Khazak Horde, marked the beginning of friendly relations between the Moghuls and the Khazaks for the next several decades.