Endothelin converting enzyme 1
Encyclopedia
Endothelin converting enzyme 1, also known as ECE1, is a enzyme
which in humans is encoded by the ECE1 gene
.
), -2 (EDN2
), and -3 (EDN3
) to biologically active peptides.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
which in humans is encoded by the ECE1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Function
Endothelin-converting enzyme-1 is involved in the proteolytic processing of endothelin-1 (EDN1Endothelin 1
Endothelin 1, also known as EDN1, is a human gene and the corresponding peptide, one of three isoforms of human endothelin.-Further reading:...
), -2 (EDN2
Endothelin 2
Endothelin 2, also known as ET-2, is a protein that in humans is encoded by the EDN2 gene.- Function :Endothelin 2 is a member of the endothelin protein family of secretory vasoconstrictive peptides. The preproprotein is processed to a short mature form which functions as a ligand for the...
), and -3 (EDN3
Endothelin 3
Endothelin-3 is a protein that in humans is encoded by the EDN3 gene.-Further reading:...
) to biologically active peptides.