Enamel organ
Encyclopedia
The enamel organ, also known as dental organ, is a cellular
Cell (biology)
The cell is the basic structural and functional unit of all known living organisms. It is the smallest unit of life that is classified as a living thing, and is often called the building block of life. The Alberts text discusses how the "cellular building blocks" move to shape developing embryos....

 aggregation seen in histologic
Histology
Histology is the study of the microscopic anatomy of cells and tissues of plants and animals. It is performed by examining cells and tissues commonly by sectioning and staining; followed by examination under a light microscope or electron microscope...

 sections of a developing tooth
Tooth development
Tooth development or odontogenesis is the complex process by which teeth form from embryonic cells, grow, and erupt into the mouth. Although many diverse species have teeth, non-human tooth development is largely the same as in humans...

. It lies above a condensation of ectomesenchymal cells called the dental papilla
Dental papilla
The dental papilla is a condensation of ectomesenchymal cells called odontoblasts, seen in histologic sections of a developing tooth. It lies below a cellular aggregation known as the enamel organ. The dental papilla appears after 8-10 weeks intra uteral life...

. Historically, enamel organ has been the term to describe this structure, but it was attempted unsuccessfully in recent years to change the name to dental organ in order to better represent its multiple functions apart from enamel
Tooth enamel
Tooth enamel, along with dentin, cementum, and dental pulp is one of the four major tissues that make up the tooth in vertebrates. It is the hardest and most highly mineralized substance in the human body. Tooth enamel is also found in the dermal denticles of sharks...

 formation.

The enamel organ functions in the formation of enamel, initiation of dentin
Dentin
Dentine is a calcified tissue of the body, and along with enamel, cementum, and pulp is one of the four major components of teeth. Usually, it is covered by enamel on the crown and cementum on the root and surrounds the entire pulp...

 formation, establishment of the shape of a tooth's crown, and establishment of the dentogingival junction.

The parts of the enamel organ include the inner enamel epithelium
Inner enamel epithelium
The inner enamel epithelium, also known as the internal enamel epithelium, is a layer of cells located on the rim nearest the dental papilla of the enamel organ in a developing tooth. This layer is first seen during the bell stage....

, outer enamel epithelium
Outer enamel epithelium
The outer enamel epithelium, also known as the external enamel epithelium, is a layer of cuboidal cells located on the periphery of the enamel organ in a developing tooth. This layer is first seen during the bell stage....

, stratum intermedium
Stratum intermedium
The stratum intermedium in a developing tooth is a layer of two or three cells between the inner enamel epithelium and the newly forming cells of the stellate reticulum. It first appears during the early bell stage of tooth development, at around the 14th week of intrauterine life. The stratum...

, and the stellate reticulum
Stellate reticulum
The stellate reticulum is a group of cells located in the center of the enamel organ of a developing tooth. These cells are star shaped and synthesize glycosaminoglycans. As glycosamingoglycans are produced, water is drawn in between the cells and stretch them apart...

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