Elsilimomab
Encyclopedia
Elsilimomab is a mouse
monoclonal antibody and an immunosuppressive drug
.
It (OPR-003) targets (and blocks) Interleukin-6.
It has undergone a number of early stage clinical trails, eg. for lymphoma
and myeloma.
It was used as a template to develop a high-affinity, antagonist, fully human anti-IL-6
mAb 1339.
Mouse
A mouse is a small mammal belonging to the order of rodents. The best known mouse species is the common house mouse . It is also a popular pet. In some places, certain kinds of field mice are also common. This rodent is eaten by large birds such as hawks and eagles...
monoclonal antibody and an immunosuppressive drug
Immunosuppressive drug
Immunosuppressive drugs or immunosuppressive agents are drugs that inhibit or prevent activity of the immune system. They are used in immunosuppressive therapy to:...
.
It (OPR-003) targets (and blocks) Interleukin-6.
It has undergone a number of early stage clinical trails, eg. for lymphoma
Lymphoma
Lymphoma is a cancer in the lymphatic cells of the immune system. Typically, lymphomas present as a solid tumor of lymphoid cells. Treatment might involve chemotherapy and in some cases radiotherapy and/or bone marrow transplantation, and can be curable depending on the histology, type, and stage...
and myeloma.
It was used as a template to develop a high-affinity, antagonist, fully human anti-IL-6
Anti-IL-6
Anti-interleukin-6 agents are a recent class of therapeutics.Interleukin-6 is relevant to many inflammatory diseases and many cancers. Hence anti-IL-6 agents have been sought....
mAb 1339.