EPS8
Encyclopedia
Epidermal growth factor receptor kinase substrate 8 is an enzyme
that in humans is encoded by the EPS8 gene
.
with BAIAP2
, SHB
, Src
, SOS1
, DVL1
, SHC1
and ABI1
.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the EPS8 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
EPS8 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with BAIAP2
BAIAP2
Brain-specific angiogenesis inhibitor 1-associated protein 2 is a protein that in humans is encoded by the BAIAP2 gene.-Interactions:BAIAP2 has been shown to interact with WASF1, EPS8, SHANK1, RAC1, WASF2, ATN1 and CDC42.-Further reading:...
, SHB
SHB (gene)
SH2 domain-containing adapter protein B is a protein that in humans is encoded by the SHB gene.-Interactions:SHB has been shown to interact with Fibroblast growth factor receptor 1, Src, Linker of activated T cells, Lymphocyte cytosolic protein 2, ZAP-70, EPS8, PIK3R1 and VAV1.-Further reading:...
, Src
Src (gene)
Proto-oncogene tyrosine-protein kinase Src is an enzyme that in humans is encoded by the SRC gene.Src is a proto-oncogene encoding a tyrosine kinase originally discovered by J. Michael Bishop and Harold E. Varmus, for which they won the 1989 Nobel Prize in Physiology or Medicine. It belongs to a...
, SOS1
SOS1
Son of sevenless homolog 1 is a protein that in humans is encoded by the SOS1 gene.Recent studies also show that mutations in Sos1 can cause Noonan syndrome and hereditary gingival fibromatosis type 1. Noonan syndrome has also been shown to be caused by mutations in KRAS and PTPN11 genes...
, DVL1
DVL1
Segment polarity protein dishevelled homolog DVL-1 is a protein that in humans is encoded by the DVL1 gene.-Interactions:DVL1 has been shown to interact with DVL3, EPS8, AXIN1 and Mothers against decapentaplegic homolog 3.-External links:...
, SHC1
SHC1
SHC-transforming protein 1 is a protein that in humans is encoded by the SHC1 gene. SHC has been found to be important in the regulation of apoptosis and drug resistance in mammalian cells....
and ABI1
ABI1
Abl interactor 1 also known as Abelson interactor 1 is a protein that in humans is encoded by the ABI1 gene.- Function :Abl interactor 1 has been found to form a complex with EPS8 and SOS1, and is thought to be involved in the transduction of signals from Ras to Rac...
.