Discriminant function
Encyclopedia
The modified Maddrey's discriminant function) was originally described by Maddrey and Boitnott to predict prognosis
in alcoholic hepatitis
. It is calculated by a simple formula:
Prospective studies have shown that, it is useful in predicting short term prognosis especially mortality within 30 days. A value more than 32 implies poor outcome with one month mortality ranging between 35% to 45%.
To calculate Maddrey discriminant function using SI units - micromol/l (i.e. not US) divide bilirubin value by 17.
Prognosis
Prognosis is a medical term to describe the likely outcome of an illness.When applied to large statistical populations, prognostic estimates can be very accurate: for example the statement "45% of patients with severe septic shock will die within 28 days" can be made with some confidence, because...
in alcoholic hepatitis
Alcoholic hepatitis
Alcoholic hepatitis is hepatitis due to excessive intake of alcohol. While distinct from cirrhosis, it is regarded as the earliest stage of alcoholic liver disease. Symptoms are jaundice, ascites , fatigue and hepatic encephalopathy...
. It is calculated by a simple formula:
Prospective studies have shown that, it is useful in predicting short term prognosis especially mortality within 30 days. A value more than 32 implies poor outcome with one month mortality ranging between 35% to 45%.
To calculate Maddrey discriminant function using SI units - micromol/l (i.e. not US) divide bilirubin value by 17.