Dihydrobiopterin
Encyclopedia
Dihydrobiopterin is a compound produced in the synthesis of dopa
, dopamine
, norepinephrine
and epinephrine
. It is restored to the required cofactor tetrahydrobiopterin
by dihydrobiopterin reductase
.
Dopa
Dopa or DOPA can refer to:* L-DOPA , used in the treatment of Parkinson's disease* D-DOPA, a chemical compound related to L-DOPA* Dopa, an angel in Enochian* Deleting Online Predators Act of 2006...
, dopamine
Dopamine
Dopamine is a catecholamine neurotransmitter present in a wide variety of animals, including both vertebrates and invertebrates. In the brain, this substituted phenethylamine functions as a neurotransmitter, activating the five known types of dopamine receptors—D1, D2, D3, D4, and D5—and their...
, norepinephrine
Norepinephrine
Norepinephrine is the US name for noradrenaline , a catecholamine with multiple roles including as a hormone and a neurotransmitter...
and epinephrine
Epinephrine
Epinephrine is a hormone and a neurotransmitter. It increases heart rate, constricts blood vessels, dilates air passages and participates in the fight-or-flight response of the sympathetic nervous system. In chemical terms, adrenaline is one of a group of monoamines called the catecholamines...
. It is restored to the required cofactor tetrahydrobiopterin
Tetrahydrobiopterin
Tetrahydrobiopterin or sapropterin is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin , melatonin, dopamine, norepinephrine ,...
by dihydrobiopterin reductase
Dihydrobiopterin reductase
Dihydrobiopterin is a compound produced in the synthesis of dopamine, norepinephrine and epinephrine through production of the intermediate 3,4-dihydroxy phenylalanine, also known as dopa...
.