David Weyhe Smith
Encyclopedia
David Weyhe Smith was an American pediatrician and dysmorphologist.

Smith was born in Oakland, California
California
California is a state located on the West Coast of the United States. It is by far the most populous U.S. state, and the third-largest by land area...

. He gained his medical degree from Johns Hopkins University School of Medicine and worked with Lawson Wilkins
Lawson Wilkins
-References:...

 in the field of pediatric endocrinology
Pediatric endocrinology
Pediatric endocrinology is a medical subspecialty dealing with variations of physical growth and sexual development in childhood, as well as diabetes and other disorders of the endocrine glands....

. He began working at the University of Wisconsin School of Medicine and Public Health
University of Wisconsin School of Medicine and Public Health
The University of Wisconsin School of Medicine and Public Health is a professional school for the study of medicine and public health at the University of Wisconsin–Madison.- History :...

 in 1958, and became a professor of pediatrics there. From 1966 until the end of his career he was at the University of Washington
University of Washington
University of Washington is a public research university, founded in 1861 in Seattle, Washington, United States. The UW is the largest university in the Northwest and the oldest public university on the West Coast. The university has three campuses, with its largest campus in the University...

, Seattle. His work in dysmorphology was recognized worldwide.

His book Recognizable Patterns of Human Malformation is considered a key work in the field. He also published five other monographs as well as nearly 200 papers. The condition known as Aase Smith syndrome is named for Smith and colleague Jon Morton Aase. Smith also co-discovered and lent his name to such conditions as Smith-Lemli-Opitz syndrome
Smith-Lemli-Opitz syndrome
Smith-Lemli-Opitz syndrome is an autosomal recessive metabolic and developmental congenital disorder that causes the inability to correctly produce or synthesize cholesterol due to a low occurrence of the 7-DHC reductace enzyme.-Symptoms:The signs and symptoms of SLOS syndrome vary widely...

, Marshall-Smith syndrome
Marshall-Smith syndrome
Marshall-Smith Syndrome, discovered in 1971 , is characterized by unusual accelerated skeletal maturation and symptoms like conspicuous physical characteristics, respiratory difficulties, and mental retardation. Cases described in the literature show a clinical variabililty regarding related...

 and others.

Fetal Alcohol Syndrome
Fetal alcohol syndrome
Fetal alcohol syndrome is a pattern of mental and physical defects that can develop in a fetus in association with high levels of alcohol consumption during pregnancy. Current research also implicates other lifestyle choices made by the prospective mother...

 was named in 1973 by Smith and Dr. Kenneth Lyons Jones, who identified a pattern of "craniofacial, limb, and cardiovascular defects associated with prenatal onset growth deficiency and developmental delay" in eight unrelated children of three ethnic groups, all born to mothers who were alcoholics.

Smith died in a car accident on a freeway in Seattle, Washington
Seattle, Washington
Seattle is the county seat of King County, Washington. With 608,660 residents as of the 2010 Census, Seattle is the largest city in the Northwestern United States. The Seattle metropolitan area of about 3.4 million inhabitants is the 15th largest metropolitan area in the country...

.

External links

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