David R. Soll
Encyclopedia
David R. Soll is a Professor of Biology at the University of Iowa. He is best known for the motion analysis of living cells, the discovery of Candida albicans
phenotypic switching and monoclonal antibody technology. He is the current director of the Developmental Studies Hybridoma Bank
, Monoclonal Antibody Research Institute, and the WM Keck Dynamic Image Analysis Facility. He is also a member of the board of directors of the Foundation for Monoclonal Antibody Research. He has published over 350 articles in various fields of biomedicine and has received more than 70 grants and contracts, founded four companies, and served on the editorial board as an associate editor or as editor of eight biomedical journals.
and graduated from Central High School (Philadelphia)
for boys in 1959. He then attended the University of Wisconsin from 1960 to 1969, receiving a BA, MS and PhD. He then served as a post-doctoral fellow and taught Introductory Biology at Brandeis University
. In 1972 he joined the Department of Biology at the University of Iowa
, as an Assistant Professor. In 1976 he became an Associate Professor and in 1982 a Full Professor. In 1989 he was awarded the Roy J. and Lucille Carver/Emil Witschi Professorship of the Biological Sciences, and in 1989 also became a Full Professor of Dentistry. In 2005, he was elected a Fellow of the American Association for the Advancement of Science
(AAAS) and in 2006 a Fellow of the American Academy of Microbiology. In 2009 he was awarded the Lucille K. George Medal from the International Society of Human and Animal Mycology. David Soll was married for 30 years to the late Michele Morice and has three children, Jacob Soll
, Samantha Soll and Benjamin Soll.
(DSHB), a NIH National Resource, Director of the W.M. Keck Dynamic Image Analysis Facility, Director of the Monoclonal Antibody Research Institute and on the board of the Foundation for Monoclonal Antibody Research. His research groups now focus on 1) the role of mating and switching in the pathogenesis of Candida albicans
, 2) cell motility and the cytoskeleton
, 3) advanced monoclonal antibody
technology and 4) cancer subgroups and cell surface antigens of cancer stem cells.
Candida albicans
Candida albicans is a diploid fungus that grows both as yeast and filamentous cells and a causal agent of opportunistic oral and genital infections in humans. Systemic fungal infections including those by C...
phenotypic switching and monoclonal antibody technology. He is the current director of the Developmental Studies Hybridoma Bank
Developmental studies hybridoma bank
The Developmental Studies Hybridoma Bank is a National Resource established by the National Institute of Child Health and Human Development to bank and distribute at cost hybridomas and cell products to the general scientific community...
, Monoclonal Antibody Research Institute, and the WM Keck Dynamic Image Analysis Facility. He is also a member of the board of directors of the Foundation for Monoclonal Antibody Research. He has published over 350 articles in various fields of biomedicine and has received more than 70 grants and contracts, founded four companies, and served on the editorial board as an associate editor or as editor of eight biomedical journals.
Background
Soll was born in Philadelphia, PennsylvaniaPennsylvania
The Commonwealth of Pennsylvania is a U.S. state that is located in the Northeastern and Mid-Atlantic regions of the United States. The state borders Delaware and Maryland to the south, West Virginia to the southwest, Ohio to the west, New York and Ontario, Canada, to the north, and New Jersey to...
and graduated from Central High School (Philadelphia)
Central High School (Philadelphia)
Central High School is a public secondary school in the Logan section of Philadelphia, Pennsylvania. Central, the second-oldest continuously public high school in the United States , was founded in 1836 and is a four-year university preparatory magnet school...
for boys in 1959. He then attended the University of Wisconsin from 1960 to 1969, receiving a BA, MS and PhD. He then served as a post-doctoral fellow and taught Introductory Biology at Brandeis University
Brandeis University
Brandeis University is an American private research university with a liberal arts focus. It is located in the southwestern corner of Waltham, Massachusetts, nine miles west of Boston. The University has an enrollment of approximately 3,200 undergraduate and 2,100 graduate students. In 2011, it...
. In 1972 he joined the Department of Biology at the University of Iowa
University of Iowa
The University of Iowa is a public state-supported research university located in Iowa City, Iowa, United States. It is the oldest public university in the state. The university is organized into eleven colleges granting undergraduate, graduate, and professional degrees...
, as an Assistant Professor. In 1976 he became an Associate Professor and in 1982 a Full Professor. In 1989 he was awarded the Roy J. and Lucille Carver/Emil Witschi Professorship of the Biological Sciences, and in 1989 also became a Full Professor of Dentistry. In 2005, he was elected a Fellow of the American Association for the Advancement of Science
American Association for the Advancement of Science
The American Association for the Advancement of Science is an international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsibility, and supporting scientific education and science outreach for the...
(AAAS) and in 2006 a Fellow of the American Academy of Microbiology. In 2009 he was awarded the Lucille K. George Medal from the International Society of Human and Animal Mycology. David Soll was married for 30 years to the late Michele Morice and has three children, Jacob Soll
Jacob Soll
Jacob Soll is a historian of early modern Europe who is researching the origins of the modern state. He is currently a professor at Rutgers University-Camden and has won the 2005 Jacques Barzun Prize in Cultural History and been awarded a Guggenheim Fellowship in 2009...
, Samantha Soll and Benjamin Soll.
Current work
He is now the Director of the Developmental Studies Hybridoma BankDevelopmental studies hybridoma bank
The Developmental Studies Hybridoma Bank is a National Resource established by the National Institute of Child Health and Human Development to bank and distribute at cost hybridomas and cell products to the general scientific community...
(DSHB), a NIH National Resource, Director of the W.M. Keck Dynamic Image Analysis Facility, Director of the Monoclonal Antibody Research Institute and on the board of the Foundation for Monoclonal Antibody Research. His research groups now focus on 1) the role of mating and switching in the pathogenesis of Candida albicans
Candida albicans
Candida albicans is a diploid fungus that grows both as yeast and filamentous cells and a causal agent of opportunistic oral and genital infections in humans. Systemic fungal infections including those by C...
, 2) cell motility and the cytoskeleton
Cytoskeleton
The cytoskeleton is a cellular "scaffolding" or "skeleton" contained within a cell's cytoplasm and is made out of protein. The cytoskeleton is present in all cells; it was once thought to be unique to eukaryotes, but recent research has identified the prokaryotic cytoskeleton...
, 3) advanced monoclonal antibody
Antibody
An antibody, also known as an immunoglobulin, is a large Y-shaped protein used by the immune system to identify and neutralize foreign objects such as bacteria and viruses. The antibody recognizes a unique part of the foreign target, termed an antigen...
technology and 4) cancer subgroups and cell surface antigens of cancer stem cells.