Cécile Vogt-Mugnier
Encyclopedia
Cecile Vogt-Mugnier was a French
neurologist
from Haute-Savoie
.
and was the student of Pierre Marie. There she met her future husband, Oskar Vogt
, when he came to Paris to work with Joseph Jules Déjérine
(and his wife, Augusta Marie Dejerine-Klumke, who collaborated with him). The Vogt couple also collaborated for a long period of time, usually with Cécile as the primary author
. The Vogts had two daughters, both accomplished scientists in their own rights. Marthe Vogt (1903–2003) was a neuropharmacologist who became a Fellow of the Royal Society and a Professor at Cambridge. Marguerite Vogt
(1913–2007) started as a developmental geneticist working in Drosophila, then moved to the US in 1950. She developed methods to culture poliovirus
with Renato Dulbecco
. She was a faculty member at The Salk Institute for Biological Studies
where she worked on viral transformation and cellular immortalization of cancer cells.
The main contribution of the Vogts was La myelocytoarchitecture du thalamus du cercopithèque from Cécile alone (1909). The great contribution of Cécile has been that the partition of the lateral region (lateral mass
) should rely on the territories (the spaces occupied) of the main afferent
s. She distinguished from back to front the lemnical radiation and a particular nucleus
, in front of it the cerebellar (prelemniscal) radiation with another nucleus and more anteriorly the "lenticular" radiation. This system still denotes today, the subdivision of the thalamus
(Percheron, 1977, Percheron et al. 1996). Her paper was followed by Die Cytoarchitechtonik des Zwishenhirns de Cercothipiteken from Friedmann (1911) traducing in cytoarchitectonic terms her partition.
A paper published in common in 1941 (Thalamus studien I to III), devoted to the human thalamus, represented an important step in partitioning and naming thalamic parts. The anatomy of the thalamus from Hassler (one of their students) was published in 1959, the year of the death of Oskar. It is not known whether the master accepted the excessive partition and unnecessary complication of this work that was an atlas dedicated to stereotacticans. The paper of 1941 was much simpler.
France
The French Republic , The French Republic , The French Republic , (commonly known as France , is a unitary semi-presidential republic in Western Europe with several overseas territories and islands located on other continents and in the Indian, Pacific, and Atlantic oceans. Metropolitan France...
neurologist
Neurologist
A neurologist is a physician who specializes in neurology, and is trained to investigate, or diagnose and treat neurological disorders.Neurology is the medical specialty related to the human nervous system. The nervous system encompasses the brain, spinal cord, and peripheral nerves. A specialist...
from Haute-Savoie
Haute-Savoie
Haute-Savoie is a French department in the Rhône-Alpes region of eastern France. It borders both Switzerland and Italy. The capital is Annecy. To the north is Lake Geneva and Switzerland; to the south and southeast are the Mont Blanc and Aravis mountain ranges and the French entrance to the Mont...
.
Family
She obtained her medical doctorate in ParisParis
Paris is the capital and largest city in France, situated on the river Seine, in northern France, at the heart of the Île-de-France region...
and was the student of Pierre Marie. There she met her future husband, Oskar Vogt
Oskar Vogt
Oskar Vogt was a German physician and neurologist. He was born in Husum - Schleswig-Holstein...
, when he came to Paris to work with Joseph Jules Déjérine
Joseph Jules Dejerine
Joseph Jules Dejerine , was a French neurologist.Joseph Jules Dejerine was born to French parents in Geneva, Switzerland, where his father was a carriage proprietor. During the Franco-Prussian War Dejerine worked as a volunteer in a Geneva Hospital and in the spring of 1871 decided to pursue his...
(and his wife, Augusta Marie Dejerine-Klumke, who collaborated with him). The Vogt couple also collaborated for a long period of time, usually with Cécile as the primary author
Author
An author is broadly defined as "the person who originates or gives existence to anything" and that authorship determines responsibility for what is created. Narrowly defined, an author is the originator of any written work.-Legal significance:...
. The Vogts had two daughters, both accomplished scientists in their own rights. Marthe Vogt (1903–2003) was a neuropharmacologist who became a Fellow of the Royal Society and a Professor at Cambridge. Marguerite Vogt
Marguerite Vogt
Marguerite Vogt, MD was a cancer biologist and virologist. She was most noted for her research on polio and cancer at the Salk Institute for Biological Studies.-Early life:...
(1913–2007) started as a developmental geneticist working in Drosophila, then moved to the US in 1950. She developed methods to culture poliovirus
Poliovirus
Poliovirus, the causative agent of poliomyelitis, is a human enterovirus and member of the family of Picornaviridae.Poliovirus is composed of an RNA genome and a protein capsid. The genome is a single-stranded positive-sense RNA genome that is about 7500 nucleotides long. The viral particle is...
with Renato Dulbecco
Renato Dulbecco
Renato Dulbecco is an Italian virologist who won a 1975 Nobel Prize in Physiology or Medicine for his work on reverse transcriptase. In 1973 he was awarded the Louisa Gross Horwitz Prize from Columbia University together with Theodore Puck and Harry Eagle. Dulbecco was the recipient of the Selman A...
. She was a faculty member at The Salk Institute for Biological Studies
Salk Institute for Biological Studies
The Salk Institute for Biological Studies is a premier independent, non-profit, scientific research institute located in La Jolla, California. It was founded in 1960 by Jonas Salk, the developer of the polio vaccine; among the founding consultants were Jacob Bronowski and Francis Crick. Building...
where she worked on viral transformation and cellular immortalization of cancer cells.
Contributions
The contributions of the Vogts are of first order in several parts of the brain and had a considerable influence on international neurological science.The main contribution of the Vogts was La myelocytoarchitecture du thalamus du cercopithèque from Cécile alone (1909). The great contribution of Cécile has been that the partition of the lateral region (lateral mass
Lateral mass
Lateral mass can refer to:* Labyrinth of ethmoid* Lateral mass of atlas...
) should rely on the territories (the spaces occupied) of the main afferent
Afferent
Afferent is an anatomical term with the following meanings:*Conveying towards a center, for example the afferent arterioles conveying blood towards the Bowman's capsule in the Kidney. Opposite to Efferent.*Something that so conducts, see Afferent nerve fiber...
s. She distinguished from back to front the lemnical radiation and a particular nucleus
Nucleus (neuroanatomy)
In neuroanatomy, a nucleus is a brain structure consisting of a relatively compact cluster of neurons. It is one of the two most common forms of nerve cell organization, the other being layered structures such as the cerebral cortex or cerebellar cortex. In anatomical sections, a nucleus shows up...
, in front of it the cerebellar (prelemniscal) radiation with another nucleus and more anteriorly the "lenticular" radiation. This system still denotes today, the subdivision of the thalamus
Thalamus
The thalamus is a midline paired symmetrical structure within the brains of vertebrates, including humans. It is situated between the cerebral cortex and midbrain, both in terms of location and neurological connections...
(Percheron, 1977, Percheron et al. 1996). Her paper was followed by Die Cytoarchitechtonik des Zwishenhirns de Cercothipiteken from Friedmann (1911) traducing in cytoarchitectonic terms her partition.
A paper published in common in 1941 (Thalamus studien I to III), devoted to the human thalamus, represented an important step in partitioning and naming thalamic parts. The anatomy of the thalamus from Hassler (one of their students) was published in 1959, the year of the death of Oskar. It is not known whether the master accepted the excessive partition and unnecessary complication of this work that was an atlas dedicated to stereotacticans. The paper of 1941 was much simpler.