Cyclofenil
Encyclopedia
Cyclofenil is a selective estrogen receptor modulator
.
It was investigated as a possible treatment for scleroderma
in the 1980s, but was found to be ineffective. Later study of its efficacy in treating Raynaud's phenomenon
in people with scleroderma also found no statistically significant
benefit.
Selective estrogen receptor modulator
Selective Estrogen Receptor Modulators are a class of compounds that act on the estrogen receptor. A characteristic that distinguishes these substances from pure receptor agonists and antagonists is that their action is different in various tissues, thereby granting the possibility to selectively...
.
It was investigated as a possible treatment for scleroderma
Scleroderma
Systemic sclerosis or systemic scleroderma is a systemic autoimmune disease or systemic connective tissue disease that is a subtype of scleroderma.-Skin symptoms:...
in the 1980s, but was found to be ineffective. Later study of its efficacy in treating Raynaud's phenomenon
Raynaud's phenomenon
In medicine, Raynaud's phenomenon is a vasospastic disorder causing discoloration of the fingers, toes, and occasionally other areas. This condition can also cause nails to become brittle with longitudinal ridges. Named for French physician Maurice Raynaud , the phenomenon is believed to be the...
in people with scleroderma also found no statistically significant
Statistical significance
In statistics, a result is called statistically significant if it is unlikely to have occurred by chance. The phrase test of significance was coined by Ronald Fisher....
benefit.