Cyclic neutropenia
Cyclic neutropenia is a form of neutropenia
Neutropenia, from Latin prefix neutro- and Greek suffix -πενία , is a granulocyte disorder characterized by an abnormally low number of neutrophils, the most important type of white blood cell...

 that tends to occur every three weeks and lasting three to six days at a time due to changing rates of cell production by the bone marrow.

It is often present among several members of the same family. Treatment includes G-CSF and usually improves after puberty.

Cyclic neutropenia is the result of autosomal dominantly inherited mutations in ELA2, the gene encoding neutrophil elastase.

See also

May be associated with oral cankers, canker sores or lesions.

External links

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