Coronary reflex
Encyclopedia
Coronary reflex is the change of coronary diameter in response to chemical, neurological or mechanical stimulation of the coronary arteries
Coronary circulation
Coronary circulation is the circulation of blood in the blood vessels of the heart muscle . The vessels that deliver oxygen-rich blood to the myocardium are known as coronary arteries...

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The coronary reflex are stimulated differently than the rest of the vascular system
Circulatory system
The circulatory system is an organ system that passes nutrients , gases, hormones, blood cells, etc...

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Chemical

  • N-nitro L-arginine
    Arginine
    Arginine is an α-amino acid. The L-form is one of the 20 most common natural amino acids. At the level of molecular genetics, in the structure of the messenger ribonucleic acid mRNA, CGU, CGC, CGA, CGG, AGA, and AGG, are the triplets of nucleotide bases or codons that codify for arginine during...

  • indomethacin
  • glibenclamide
  • tetraethylammonium chloride
  • caffine

Causes of coronary dilation

Cocaine abuse
Cocaine
Cocaine is a crystalline tropane alkaloid that is obtained from the leaves of the coca plant. The name comes from "coca" in addition to the alkaloid suffix -ine, forming cocaine. It is a stimulant of the central nervous system, an appetite suppressant, and a topical anesthetic...

 frequently can cause a coronary spasm, resulting in a spontaneous myocardial infarction
Myocardial infarction
Myocardial infarction or acute myocardial infarction , commonly known as a heart attack, results from the interruption of blood supply to a part of the heart, causing heart cells to die...

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Chemical

  • Versed (Midazolam): a coronary dilator. In midazolam's presence, dilation was unaffected by N-nitro L-arginine, indomethacin and glibenclamide.
  • Tetraethylammonium chloride, an inhibitor of the BKCa K+ channel (a high conductance Ca2+-sensitive K+ channel), dose dependently attenuated the vasodilating effect of midazolam

  • Estrogen has been shown to abolish abnormal cold-induced coronary constriction.
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