Corneal neovascularization is the excessive ingrowth of blood vessels from the limbal vascular plexus into the cornea

Cornea

The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber. Together with the lens, the cornea refracts light, with the cornea accounting for approximately two-thirds of the eye's total optical power. In humans, the refractive power of the cornea is...

, caused by a low reception of oxygen, which is generally not received from the bloodstream, but through the air. One of the most common causes is contact lens

Contact lens

A contact lens, or simply contact, is a lens placed on the eye. They are considered medical devices and can be worn to correct vision, for cosmetic or therapeutic reasons. In 2004, it was estimated that 125 million people use contact lenses worldwide, including 28 to 38 million in the United...

 wear, and to a greater extent, continued use of extended wear contacts. The condition could threaten one's eyesight in the elevated stages, which is one of the primary reasons eye care physicians strongly recommend routine (annual) exams for contact lens patients.

Reduction of neovascularization has been achieved in rats by the topical instillation of commercially available triamcinolone

Triamcinolone

Triamcinolone is a long-acting synthetic corticosteroid given orally, by injection, inhalation, or as a topical ointment or cream....

 and doxycycline

Doxycycline

Doxycycline INN is a member of the tetracycline antibiotics group, and is commonly used to treat a variety of infections. Doxycycline is a semisynthetic tetracycline invented and clinically developed in the early 1960s by Pfizer Inc. and marketed under the brand name Vibramycin. Vibramycin...

.