Connexin-43 internal ribosome entry site (IRES)
Encyclopedia
The connexin-43 internal ribosome entry site (IRES) is an RNA element
present in the 5' UTR
of the mRNA of connexin-43 and allows cap-independent translation. The connexin-43 internal ribosome entry site
(IRES) allows cap independent translation during conditions such as heat shock and stress.
Cis-regulatory element
A cis-regulatory element or cis-element is a region of DNA or RNA that regulates the expression of genes located on that same molecule of DNA . This term is constructed from the Latin word cis, which means "on the same side as". These cis-regulatory elements are often binding sites for one or...
present in the 5' UTR
Five prime untranslated region
A messenger ribonucleic acid molecule codes for a protein through translation. The mRNA also contains regions that are not translated: in eukaryotes these include the 5' untranslated region, 3' untranslated region, 5' cap and poly-A tail....
of the mRNA of connexin-43 and allows cap-independent translation. The connexin-43 internal ribosome entry site
Internal ribosome entry site
An internal ribosome entry site, abbreviated IRES, is a nucleotide sequence that allows for translation initiation in the middle of a messenger RNA sequence as part of the greater process of protein synthesis...
(IRES) allows cap independent translation during conditions such as heat shock and stress.