Co-tenidone is a non-proprietary name used to denote a combination of atenolol and chlortalidone

Chlortalidone

Chlortalidone or chlorthalidone is a diuretic drug used to treat hypertension, originally marketed as Hygroton in the USA. It is described as a thiazide diuretic...

. Co-tenidone is used in the treatment of hypertension

Hypertension

Hypertension or high blood pressure is a cardiac chronic medical condition in which the systemic arterial blood pressure is elevated. What that means is that the heart is having to work harder than it should to pump the blood around the body. Blood pressure involves two measurements, systolic and...

. The use of β-blockers in hypertension was downgraded in June 2006 in the United Kingdom to fourth-line because they perform less well than other drugs, and because atenolol, the most frequently used β-blocker, at usual doses carries an unacceptable risk of provoking type 2 diabetes

Diabetes mellitus type 2

Diabetes mellitus type 2formerly non-insulin-dependent diabetes mellitus or adult-onset diabetesis a metabolic disorder that is characterized by high blood glucose in the context of insulin resistance and relative insulin deficiency. Diabetes is often initially managed by increasing exercise and...

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Formulation

Two strengths of co-tenidone are currently available in the UK:

• 50 mg atenolol and 12.5 mg chlortalidone , BAN of Co-tenidone 50/12.5
• 100 mg atenolol and 25 mg chlortalidone , BAN of Co-tenidone 100/25