Clenoliximab
Encyclopedia
Clenoliximab is a monoclonal antibody against CD4
. It acts as an immunomodulator
and has been investigated for the treatment of rheumatoid arthritis
.
The drug is a chimeric antibody from Macaca irus and Homo sapiens.
CD4
CD4 is a glycoprotein expressed on the surface of T helper cells, monocytes, macrophages, and dendritic cells. It was discovered in the late 1970s and was originally known as leu-3 and T4 before being named CD4 in 1984...
. It acts as an immunomodulator
Immunomodulator
An immunomodulator, also known as an immunotherapy is a substance which has an effect on the immune system.- Immunosuppressants :Inhibits immune response in organ transplantation and autoimmune diseases.- Immunostimulants :...
and has been investigated for the treatment of rheumatoid arthritis
Rheumatoid arthritis
Rheumatoid arthritis is a chronic, systemic inflammatory disorder that may affect many tissues and organs, but principally attacks synovial joints. The process produces an inflammatory response of the synovium secondary to hyperplasia of synovial cells, excess synovial fluid, and the development...
.
The drug is a chimeric antibody from Macaca irus and Homo sapiens.