The cleithrum is a membrane bone which first appears as part of the skeleton in primitive bony fish

Osteichthyes

Osteichthyes , also called bony fish, are a taxonomic group of fish that have bony, as opposed to cartilaginous, skeletons. The vast majority of fish are osteichthyes, which is an extremely diverse and abundant group consisting of over 29,000 species...

, where it runs vertically along the scapula

Scapula

In anatomy, the scapula , omo, or shoulder blade, is the bone that connects the humerus with the clavicle ....

. Its name is derived from Greek κλειθρον = "key (lock)

Key (lock)

A key is an instrument that is used to operate a lock. A typical key consists of two parts: the blade, which slides into the keyway of the lock and distinguishes between different keys, and the bow, which is left protruding so that torque can be applied by the user. The blade is usually intended to...

", by analogy with "clavicle

Clavicle

In human anatomy, the clavicle or collar bone is a long bone of short length that serves as a strut between the scapula and the sternum. It is the only long bone in body that lies horizontally...

" from Latin clavicula = "little key".

In modern fishes, the cleithrum is a large bone that extends upwards from the base of the pectoral fin and anchors to the cranium above the gills, forming the posterior edge of the gill chamber. The bone has scientific use as a means to determine the age of fishes.

The lobe-finned fishes share this arrangement. In the earliest amphibians

Labyrinthodontia

Labyrinthodontia is an older term for any member of the extinct subclass of amphibians, which constituted some of the dominant animals of Late Paleozoic and Early Mesozoic times . The group is ancestral to all extant landliving vertebrates, and as such constitutes an evolutionary grade rather...

 however, the cleithrum/clavicle complex came free of the skull roof

Skull roof

The skull roof , or the roofing bones of the skull are a set of bones covering the brain, eyes and nostrils in bony fishes and all land living vertebrates. The bones are derived from dermal bone, hence the alternative name dermatocranium...

, allowing for a movable neck. The cleithrum disappeared early in the evolution of reptile

Reptile

Reptiles are members of a class of air-breathing, ectothermic vertebrates which are characterized by laying shelled eggs , and having skin covered in scales and/or scutes. They are tetrapods, either having four limbs or being descended from four-limbed ancestors...

s, and is not found in any living amniote

Amniote

The amniotes are a group of tetrapods that have a terrestrially adapted egg. They include synapsids and sauropsids , as well as their fossil ancestors. Amniote embryos, whether laid as eggs or carried by the female, are protected and aided by several extensive membranes...

s.