Clastogenic
Encyclopedia
Clastogenic is an adjective that describes the ability of an agent or process to act as a clastogen
—an agent or process giving rise to or inducing disruption or breakages of chromosomes.
Clastogens are mutagens which cause chromosome effects including breaks, rearrangements and changes in number.
Clastogen
A clastogen is a material that can cause breaks in chromosomes, leading to sections of the chromosome being deleted, added, or rearranged. This is a form of mutagenesis, and can lead to carcinogenesis, as cells that are not killed by the clastogenic effect may become cancerous...
—an agent or process giving rise to or inducing disruption or breakages of chromosomes.
Biology
Clastogenic in biology is a term which refers to an agent or process giving rise to or inducing disruption or breakages, as of chromosomes.- Illustrative sentence: "This leads to the conclusion that a chemical that fails to induce a significant response in an in vitro clastogenicity assay is unlikely to be clastogenic in vivo, in bone marrow assays."
Clastogens are mutagens which cause chromosome effects including breaks, rearrangements and changes in number.
Geology
Clastogenic in volcanic eruptions is a term which refers to an agent or process giving rise to or inducing disruption of the type of ejecta.- Illustrative sentence: "The complex features of this eruption can be explained by rapid deposition of coarse pyroclasts near the vent and the subsequent flowage of clastogenic lavas which were accompanied by a high eruption plume generating pumice falls and/or pyroclastic flows."