Chronic mucocutaneous candidiasis
Encyclopedia
Chronic mucocutaneous candidiasis is an immune disorder
of T cell
s. It is characterized by chronic infections with Candida
that are limited to mucosal surfaces, skin, and nails. However, it can also be associated with other types of infections, such as human papilloma virus.
An association with chromosome 2 has been identified.
Types include:
Immune disorder
An immune disorder is a dysfunction of the immune system. These disorders can be characterized in several different ways:* By the component of the immune system affected* By whether the immune system is overactive or underactive...
of T cell
T cell
T cells or T lymphocytes belong to a group of white blood cells known as lymphocytes, and play a central role in cell-mediated immunity. They can be distinguished from other lymphocytes, such as B cells and natural killer cells , by the presence of a T cell receptor on the cell surface. They are...
s. It is characterized by chronic infections with Candida
Candida (genus)
Candida is a genus of yeasts. Many species are harmless commensals or endosymbionts of animal hosts including humans, but other species, or harmless species in the wrong location, can cause disease. Candida albicans can cause infections in humans and other animals, especially in immunocompromised...
that are limited to mucosal surfaces, skin, and nails. However, it can also be associated with other types of infections, such as human papilloma virus.
An association with chromosome 2 has been identified.
Types include:
| Type | OMIM | Gene | Locus |
|---|---|---|---|
| CANDF1 | ? | 2p | |
| CANDF2 | CARD9 CARD9 Caspase recruitment domain-containing protein 9 is an adaptor protein that in humans is encoded by the CARD9 gene.- Function :CARD9 is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain... |
9q34.3 | |
| CANDF3 | ? | 11 | |
| CANDF4 | CLEC7A CLEC7A C-type lectin domain family 7 member A is a protein that in humans is encoded by the CLEC7A gene.-Further reading:... |
12p13.2-p12.3 | |
| CANDF5 | IL17RA IL17RA Interleukin 17 receptor A, also known as IL17RA and CDw217 , is a human gene.... |
22q11 | |
| CANDF6 | IL17F | 6p12 |