Chordamesoderm
Encyclopedia
Chordamesoderm, also known as axial mesoderm, is a type of mesoderm
Mesoderm
In all bilaterian animals, the mesoderm is one of the three primary germ cell layers in the very early embryo. The other two layers are the ectoderm and endoderm , with the mesoderm as the middle layer between them.The mesoderm forms mesenchyme , mesothelium, non-epithelial blood corpuscles and...

 that lies along the central axis, under the neural tube
Neural tube
In the developing vertebrate, the neural tube is the embryo's precursor to the central nervous system, which comprises the brain and spinal cord...

.

  • will give rise to notochord
  • starts as the notochordal process, whose formation finishes at day 20.
  • important not only in forming the notochord itself but also in inducing development of the overlying ectoderm into the neural tube
  • will eventually induce the formation of vertebral bodies.
  • ventral floor of the notochordal process fuses with endoderm.
  • The notochord will form the nucleus pulposus
    Nucleus pulposus
    Nucleus pulposus is the jelly-like substance in the middle of the spinal disc. It is the remnant of the notochord . It functions to distribute hydraulic pressure in all directions within each disc under compressive loads. The nucleus pulposus consists of chondrocyte-like cells, collagen fibrils,...

     of interverterbral discs. There is some discussion as to whether these cells contributed from the notochord are replaced by others from the adjacent mesoderm.

It gives rise to the notochordal process which later becomes the notochord
Notochord
The notochord is a flexible, rod-shaped body found in embryos of all chordates. It is composed of cells derived from the mesoderm and defines the primitive axis of the embryo. In some chordates, it persists throughout life as the main axial support of the body, while in most vertebrates it becomes...


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Category:Embryology
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