Charles du Maine was the third son of Louis II of Anjou and Yolande of Aragon

Yolande of Aragon

Yolande of Aragon, , was a throne claimant and titular queen regnant of Aragon, titular queen consort of Naples, Duchess of Anjou, Countess of Provence, and regent of Provence during the minority of her son...

.

In 1434, he married Cobella Ruffo (d. 1442), Countess of Montalto and Corigliano, he had one son:

• Jean Louis Marin, died as an infant

In 1437, he took up arms on behalf of Charles VII of France

Charles VII of France

Charles VII , called the Victorious or the Well-Served , was King of France from 1422 to his death, though he was initially opposed by Henry VI of England, whose Regent, the Duke of Bedford, ruled much of France including the capital, Paris...

, participating in the capture of Montereau

Montereau-Fault-Yonne

Montereau-Fault-Yonne, or simply Montereau, is a commune in the Seine-et-Marne department in the Île-de-France region in north-central France.-Name:...

, and that of Pontoise

Pontoise

Pontoise is a commune in the northwestern suburbs of Paris, France. It is located from the centre of Paris, in the "new town" of Cergy-Pontoise.-Administration:...

 in 1441. At this time, his brother René

René I of Naples

René of Anjou , also known as René I of Naples and Good King René , was Duke of Anjou, Count of Provence , Count of Piedmont, Duke of Bar , Duke of Lorraine , King of Naples , titular King of Jerusalem...

 ceded to him the County of Maine. He continued to take part in Charles' campaigns.

By his second marriage in 1443 to Isabelle of Saint-Pol (d. 1472), daughter of Peter of Luxembourg, Count of Saint-Pol

Peter of Luxembourg, Count of Saint-Pol

Peter of Luxembourg was a son of John of Luxembourg, Lord of Beauvoir and his wife Marguerite of Enghien. His inheritance included the counties of Brienne, Conversano and Saint-Pol.- Family :...

, he had two children:

• Louise (1445–1477, Carlat), married 1462 at Poitiers
  Poitiers
  Poitiers is a city on the Clain river in west central France. It is a commune and the capital of the Vienne department and of the Poitou-Charentes region. The centre is picturesque and its streets are interesting for predominant remains of historical architecture, especially from the Romanesque...
  
   Jacques d'Armagnac, Duke of Nemours
  Jacques d'Armagnac, Duke of Nemours
  Jacques d'Armagnac, duke of Nemours was the son of Bernard d'Armagnac, count of Pardiac, and Eleanor of Bourbon-La Marche....
  
   (d. 1477)
• Charles IV, Duke of Anjou
  Charles IV, Duke of Anjou
  Charles IV, Duke of Anjou, also Charles of Maine, Count of Le Maine and Guise was the son of the Angevin prince Charles of Le Maine, Count of Maine, who was the youngest son of Louis II of Anjou and Yolande of Aragon, Queen of Four Kingdoms.He succeeded his father as Count of Maine, Guise, Mortain...
  
   (1446–1481)

A dispute over the county of Guise between Charles and Isabelle's brother Louis de Luxembourg, Count of Saint-Pol

Louis de Luxembourg, Count of Saint-Pol

Louis de Luxembourg, Count of Saint-Pol, of Brienne, de Ligny, and Conversano belonged to the Ligny branch of the House of Luxemburg and was Constable of France....

 was settled by settling it upon Isabelle as a dowry.

He led the rearguard for King Louis XI

Louis XI of France

Louis XI , called the Prudent , was the King of France from 1461 to 1483. He was the son of Charles VII of France and Mary of Anjou, a member of the House of Valois....

 at the Battle of Montlhéry

Battle of Montlhéry

The Battle of Montlhéry was fought between Louis XI and the League of the Public Weal on the 16th of July 1465 in proximity to Longpont-sur-Orge. It had no clear winner and therefore didn't decide the war.-Insurgency of the Vassal countries:...

.