Center for Cerebrovascular Research
Encyclopedia
The Center for Cerebrovascular Research at the University of California, San Francisco
is a collective of faculty and staff investigating matters related to cerebral circulation, particularly cerebrovascular disease
resulting from narrowing of major blood vessels in the brain and vascular malformation
of the brain.
While research offices are located on Parnassus campus, San Francisco General Hospital
hosts the center's laboratories and facilities. The center coordinates with additional faculty in various fields of neuroscience
and vascular biology. Sponsors include the National Institute of Neurological Disorders and Stroke
and the UCSF departments of Anesthesia, Neurological Surgery and Neurology.
NIH Announces Expansion of Rare Diseases Clinical Research Network
Nineteen New and Returning Consortia to be Awarded $117 Million
University of California, San Francisco
The University of California, San Francisco is one of the world's leading centers of health sciences research, patient care, and education. UCSF's medical, pharmacy, dentistry, nursing, and graduate schools are among the top health science professional schools in the world...
is a collective of faculty and staff investigating matters related to cerebral circulation, particularly cerebrovascular disease
Cerebrovascular disease
Cerebrovascular disease is a group of brain dysfunctions related to disease of the blood vessels supplying the brain. Hypertension is the most important cause; it damages the blood vessel lining, endothelium, exposing the underlying collagen where platelets aggregate to initiate a repairing process...
resulting from narrowing of major blood vessels in the brain and vascular malformation
Vascular malformation
Vascular malformation is a term used to refer to blood vessel abnormalities. Vascular malformations and vascular tumors both belong to vascular anomaliesThere are many types, but the most common is arteriovenous malformation....
of the brain.
While research offices are located on Parnassus campus, San Francisco General Hospital
San Francisco General Hospital
San Francisco General Hospital is the main public hospital in San Francisco, California, and the only Level I Trauma Center serving San Francisco and northern San Mateo County...
hosts the center's laboratories and facilities. The center coordinates with additional faculty in various fields of neuroscience
Neuroscience
Neuroscience is the scientific study of the nervous system. Traditionally, neuroscience has been seen as a branch of biology. However, it is currently an interdisciplinary science that collaborates with other fields such as chemistry, computer science, engineering, linguistics, mathematics,...
and vascular biology. Sponsors include the National Institute of Neurological Disorders and Stroke
National Institute of Neurological Disorders and Stroke
The National Institute of Neurological Disorders and Stroke is a part of the U.S. National Institutes of Health . It conducts and funds research on brain and nervous system disorders and has a budget of just over US$1.5 billion...
and the UCSF departments of Anesthesia, Neurological Surgery and Neurology.
History
The Center for Cerebrovascular Research was established at the University of California San Francisco in 2000.Clinical trials
The CCR is a participating in the first attempt at studying brain arteriovenous malformation (BAVM) management using a randomized controlled clinical trial. This multi-center trial (ARUBA: A Randomized Trial of Unruptured Brain Arteriovenous Malformations) has been funded by the National Institute of Neurological Disorders and Stroke (NINDS). The goal of the project is to test the null hypothesis that treatment, by means of interventional procedures, surgery, or radiotherapy offers no difference in the risk of death or symptomatic stroke, and no better functional outcome than does conservative management at five years from discovery of an unruptured brain arteriovenous malformation (BAVM).Specific areas of research
- Arteriovenous malformationArteriovenous malformationArteriovenous malformation or AVM is an abnormal connection between veins and arteries, usually congenital. This pathology is widely known because of its occurrence in the central nervous system, but can appear in any location. An arteriovenous malformation is a vascular anomaly. It is a...
- Subarachnoid hemorrhageSubarachnoid hemorrhageA subarachnoid hemorrhage , or subarachnoid haemorrhage in British English, is bleeding into the subarachnoid space—the area between the arachnoid membrane and the pia mater surrounding the brain...
- Cerebral aneurysmCerebral aneurysmA cerebral or brain aneurysm is a cerebrovascular disorder in which weakness in the wall of a cerebral artery or vein causes a localized dilation or ballooning of the blood vessel.- Signs and symptoms :...
Accolades
William L. Young, M.D., Recipient of the 2009 Excellence in Research AwardNIH Announces Expansion of Rare Diseases Clinical Research Network
Nineteen New and Returning Consortia to be Awarded $117 Million