Cardiogenesis
Encyclopedia
Cardiogenesis Corporation (OtherOTC:CGCP) is a medical device company specializing in products for the treatment of chronic cardiac ischemia
.
The company's Ho:YAG laser system and disposable fiber-optic accessories are used to perform an FDA
-cleared surgical procedure known as Transmyocardial revascularization
(TMR). As a surgical tool, Holmium:YAG is used in a variety of medical specialties including orthopedics, urology, ENT, gynecology, gastroenterology and cardiac surgery. The fiberoptic delivery of the Ho:YAG laser makes available the minimally invasive delivery of the prescribed energy to the surgical site via ports or small incisions.
Founded in 1989, Cardiogenesis is headquartered in Irvine, California
and sells its products primarily in the United States with clinical centers in Europe and Asia. As of 2011, it has approximately 30 direct employees with stated past year revenue over $11,000,000.
The term cardiogenesis is defined as the development of the heart in the embryo. The corporation derives its name from this word and the clinical support that TMR stimulates growth of new blood vessels in heart tissue.
in patients with diffuse coronary artery disease(CAD). Patients suffering from chronic angina (chest pain) are generally managed aggressively with medications to help alleviate their symptoms and frequently receive multiple coronary interventions and even bypass surgery over the course of the advancement of their disease. When chest pain continues in spite of treatments, the condition is considered, “refractory angina.”
Coronary artery disease remains a leading cause of death for persons over the age of 65 in the United States. It is estimated that in the United States 100,000-200,000 symptomatic patients are diagnosed each year with refractory angina but are not candidates for further intervention or bypass surgery. A contemporary study indicates that as many of 3 out of 10 patients with CAD may have incomplete revascularization.
In addition to the TMR procedure, Cardiogenesis is developing proprietary catheter-based systems for the delivery of biologics, such as stem cells, as an adjunctive therapy for this patient population.
Ischemia
In medicine, ischemia is a restriction in blood supply, generally due to factors in the blood vessels, with resultant damage or dysfunction of tissue. It may also be spelled ischaemia or ischæmia...
.
The company's Ho:YAG laser system and disposable fiber-optic accessories are used to perform an FDA
Food and Drug Administration
The Food and Drug Administration is an agency of the United States Department of Health and Human Services, one of the United States federal executive departments...
-cleared surgical procedure known as Transmyocardial revascularization
Transmyocardial revascularization
Transmyocardial laser revascularization is a new procedure used to treat inoperable heart disease in people with persistent angina that isn't relieved by any other method.- Introduction :...
(TMR). As a surgical tool, Holmium:YAG is used in a variety of medical specialties including orthopedics, urology, ENT, gynecology, gastroenterology and cardiac surgery. The fiberoptic delivery of the Ho:YAG laser makes available the minimally invasive delivery of the prescribed energy to the surgical site via ports or small incisions.
Founded in 1989, Cardiogenesis is headquartered in Irvine, California
California
California is a state located on the West Coast of the United States. It is by far the most populous U.S. state, and the third-largest by land area...
and sells its products primarily in the United States with clinical centers in Europe and Asia. As of 2011, it has approximately 30 direct employees with stated past year revenue over $11,000,000.
The term cardiogenesis is defined as the development of the heart in the embryo. The corporation derives its name from this word and the clinical support that TMR stimulates growth of new blood vessels in heart tissue.
Market
Cardiogenesis products focus on the treatment of refractory anginaAngina
Angina pectoris, commonly known as angina, is chest pain due to ischemia of the heart muscle, generally due to obstruction or spasm of the coronary arteries . Coronary artery disease, the main cause of angina, is due to atherosclerosis of the cardiac arteries...
in patients with diffuse coronary artery disease(CAD). Patients suffering from chronic angina (chest pain) are generally managed aggressively with medications to help alleviate their symptoms and frequently receive multiple coronary interventions and even bypass surgery over the course of the advancement of their disease. When chest pain continues in spite of treatments, the condition is considered, “refractory angina.”
Coronary artery disease remains a leading cause of death for persons over the age of 65 in the United States. It is estimated that in the United States 100,000-200,000 symptomatic patients are diagnosed each year with refractory angina but are not candidates for further intervention or bypass surgery. A contemporary study indicates that as many of 3 out of 10 patients with CAD may have incomplete revascularization.
In addition to the TMR procedure, Cardiogenesis is developing proprietary catheter-based systems for the delivery of biologics, such as stem cells, as an adjunctive therapy for this patient population.