Caldesmon
Encyclopedia
Caldesmon is a protein
that in humans is encoded by the CALD1 gene
.
Caldesmon is a calmodulin binding protein. Like calponin
, caldesmon tonically inhibits the ATPase activity of myosin in smooth muscle.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the CALD1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Caldesmon is a calmodulin binding protein. Like calponin
Calponin
Calponin is a calcium binding protein. Calponin tonically inhibits the ATPase activity of myosin in smooth muscle. Phosphorylation of calponin by a protein kinase, which is dependent upon calcium binding to calmodulin, releases the calponin's inhibition of the smooth muscle ATPase.- Sturcture and...
, caldesmon tonically inhibits the ATPase activity of myosin in smooth muscle.