CUL4A
Encyclopedia
Cullin-4A is a protein
that in humans is encoded by the CUL4A gene
.
with Merlin
, DDB2
, CAND1
, RBX1
, DDB1
and P21
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the CUL4A gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
CUL4A has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with Merlin
Merlin (protein)
Merlin is a cytoskeletal protein. In humans, it is a tumor suppressor protein involved in Neurofibromatosis type II. Sequence data reveal its similarity to the ERM protein family....
, DDB2
DDB2
DNA damage-binding protein 2 is a protein that in humans is encoded by the DDB2 gene.-Interactions:DDB2 has been shown to interact with CUL4A, CUL4B and DDB1.-External Links:* -Further reading:...
, CAND1
CAND1
Cullin-associated NEDD8-dissociated protein 1 is a protein that in humans is encoded by the CAND1 gene.-Interactions:CAND1 has been shown to interact with CUL4A, CUL4B, RBX1, CUL1, DCUN1D1, CUL3 and CUL2.-Further reading:...
, RBX1
RBX1
RING-box protein 1 is a protein that in humans is encoded by the RBX1 gene.-Interactions:RBX1 has been shown to interact with CUL4A, CAND1, CUL1, CUL2, P70-S6 Kinase 1, DCUN1D1, CUL5 and CUL7.-Further reading:...
, DDB1
DDB1
DNA damage-binding protein 1 is a protein that in humans is encoded by the DDB1 gene.- Function :This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide excision repair...
and P21
P21
p21 / WAF1 also known as cyclin-dependent kinase inhibitor 1 or CDK-interacting protein 1 is a protein that in humans is encoded by the CDKN1A gene located on chromosome 6 .- Function :...
.