The COmponent Detection Algorithm (CODA) is a name for a type of LC-MS

Liquid chromatography-mass spectrometry

Liquid chromatography–mass spectrometry is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry. LC-MS is a powerful technique used for many applications which has very high...

 and chemometrics

Chemometrics

Chemometrics is the science of extracting information from chemical systems by data-driven means. It is a highly interfacial discipline, using methods frequently employed in core data-analytic disciplines such as multivariate statistics, applied mathematics, and computer science, in order to...

 software algorithm focused on detecting peaks in noisy chromatogram

Mass chromatogram

A mass chromatogram is a representation of mass spectrometry data as a chromatogram, where the x-axis represents time and the y-axis represents signal intensity. The source data contains mass information; however, it is not graphically represented in a mass chromatogram in favor of visualizing...

s (TIC) often obtained using the electospray ionization technique.

The implementation of the algorithm from a mass spectrometry software to another differs. Some implementations need clean chromatograms to substruct background.