COL4A3BP
Encyclopedia
Collagen type IV alpha-3-binding protein, ceramide
transfer protein (CERT) or StAR-related lipid transfer protein 11 (STARD11) is a protein
that in humans is encoded by the COL4A3BP gene
. The protein contains a pleckstrin homology domain
at its amino terminus and a START domain
towards the end of the molecule. It is a member of the StarD2 subfamily of START domain proteins.
Ceramide
Ceramides are a family of lipid molecules. A ceramide is composed of sphingosine and a fatty acid. Ceramides are found in high concentrations within the cell membrane of cells. They are one of the component lipids that make up sphingomyelin, one of the major lipids in the lipid bilayer...
transfer protein (CERT) or StAR-related lipid transfer protein 11 (STARD11) is a protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the COL4A3BP gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
. The protein contains a pleckstrin homology domain
Pleckstrin homology domain
Pleckstrin homology domain is a protein domain of approximately 120 amino acids that occurs in a wide range of proteins involved in intracellular signaling or as constituents of the cytoskeleton....
at its amino terminus and a START domain
StAR-related transfer domain
START is a lipid-binding domain in StAR, HD-ZIP and signalling proteins. The archetypical domain is found in StAR , a mitochondrial protein that is synthesized in steroid-producing cells. StAR and initiates steroid production by mediating the delivery of cholesterol to the first enzyme in...
towards the end of the molecule. It is a member of the StarD2 subfamily of START domain proteins.