CD49d
Encyclopedia
CD49d is an integrin
alpha subunit. It makes up half of the α4β1 lymphocyte homing receptor.
with LGALS8
and Paxillin
.
Integrin
Integrins are receptors that mediate attachment between a cell and the tissues surrounding it, which may be other cells or the ECM. They also play a role in cell signaling and thereby regulate cellular shape, motility, and the cell cycle....
alpha subunit. It makes up half of the α4β1 lymphocyte homing receptor.
Interactions
CD49d has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with LGALS8
LGALS8
Galectin-8 is a protein that in humans is encoded by the LGALS8 gene.-Interactions:LGALS8 has been shown to interact with CD49d, CD29 and CD49c.-Further reading:...
and Paxillin
Paxillin
Paxillin is a signal transduction adaptor protein discovered in 1990 in the laboratory of Keith Burridge and should not be confused with the neurotoxin paxilline. The C-terminal region of paxillin contains four LIM domains that target paxillin to focal adhesions, it is presumed through a direct...
.
External links
- ITGA4 Info with links in the Cell Migration Gateway