Bucindolol
Encyclopedia
Bucindolol is a non-selective
beta blocker
with additional weak alpha-blocking
properties and some intrinsic sympathomimetic activity. It was under review by the FDA
in the United States
for the treatment of heart failure in 2009 .
Binding selectivity
Binding selectivity refers to the differing affinities with which different ligands bind to a substrate forming a complex. A selectivity coefficient is the equilibrium constant for the reaction of displacement by one ligand of another ligand in a complex with the substrate...
beta blocker
Beta blocker
Beta blockers or beta-adrenergic blocking agents, beta-adrenergic antagonists, beta-adrenoreceptor antagonists or beta antagonists, are a class of drugs used for various indications. They are particularly for the management of cardiac arrhythmias, cardioprotection after myocardial infarction ,...
with additional weak alpha-blocking
Alpha blocker
Alpha-1 blockers constitute a variety of drugs which block α1-adrenergic receptors in arteries and smooth muscles.-Pharmacology:...
properties and some intrinsic sympathomimetic activity. It was under review by the FDA
Food and Drug Administration
The Food and Drug Administration is an agency of the United States Department of Health and Human Services, one of the United States federal executive departments...
in the United States
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...
for the treatment of heart failure in 2009 .