BioCryst Pharmaceuticals
Encyclopedia
BioCryst Pharmaceuticals, Inc. is a pharmaceutical company headquartered in Birmingham, Alabama
Birmingham, Alabama
Birmingham is the largest city in Alabama. The city is the county seat of Jefferson County. According to the 2010 United States Census, Birmingham had a population of 212,237. The Birmingham-Hoover Metropolitan Area, in estimate by the U.S...

. The company focuses on cancer, autoimmune diseases, and viral infections. The company's most notable function has been the production of the antiviral medication Peramivir, which was approved by the FDA for emergency use in the treatment of drug resistant influenza A virus subtype H1N1.

History

The company was founded in 1986 by Charles E. Bugg, Ph.D. and John A. Montgomery, Ph.D. In March 1994, BioCryst became a public company
Public company
This is not the same as a Government-owned corporation.A public company or publicly traded company is a limited liability company that offers its securities for sale to the general public, typically through a stock exchange, or through market makers operating in over the counter markets...

 when it completed an Initial Public Offering
Initial public offering
An initial public offering or stock market launch, is the first sale of stock by a private company to the public. It can be used by either small or large companies to raise expansion capital and become publicly traded enterprises...

 by listing its shares on the NASDAQ
NASDAQ
The NASDAQ Stock Market, also known as the NASDAQ, is an American stock exchange. "NASDAQ" originally stood for "National Association of Securities Dealers Automated Quotations". It is the second-largest stock exchange by market capitalization in the world, after the New York Stock Exchange. As of...

 stock exchange. In 2008 the company was named one of the fastest growing companies by Deloitte & Touche in its 2008 list of Technology Fast 500.

In October 2010, BioCryst announced its headquarters would move to Durham, North Carolina
Durham, North Carolina
Durham is a city in the U.S. state of North Carolina. It is the county seat of Durham County and also extends into Wake County. It is the fifth-largest city in the state, and the 85th-largest in the United States by population, with 228,330 residents as of the 2010 United States census...

, where the company has had an office since 2006.

Pipeline

  • Forodesine
    Forodesine
    Forodesine is a transition-state analog inhibitor of purine nucleoside phosphorylase under development for the treatment of relapsed B-cell chronic lymphocytic leukemia...

     HCl, investigational purine nucleoside phosphorylase
    Purine nucleoside phosphorylase
    Purine nucleoside phosphorylase also known as PNPase and inosine phosphorylase is an enzyme that in humans is encoded by the NP gene.- Function :Purine nucleoside phosphorylase is an enzyme involved in purine metabolism...

     (PNP) inhibitor for the treatment of T- and B-cell mediated disorders.
  • BCX-4208/R3421, a second generation purine nucleoside phosphorylase
    Purine nucleoside phosphorylase
    Purine nucleoside phosphorylase also known as PNPase and inosine phosphorylase is an enzyme that in humans is encoded by the NP gene.- Function :Purine nucleoside phosphorylase is an enzyme involved in purine metabolism...

     inhibitor with applications in autoimmune diseases.
  • Peramivir
    Peramivir
    Peramivir is an experimental antiviral drug developed by BioCryst Pharmaceuticals for the treatment of influenza. It has been authorized for the emergency use of treatment of certain hospitalized patients with known or suspected 2009 H1N1 influenza....

    is an experimental antiviral drug being developed for the treatment of influenza.

External links

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