Beta-adrenergic agonist
Encyclopedia
Beta-adrenergic agonists are adrenergic agonists which act upon the beta receptors.
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β1 agonists
β1 agonists: stimulates adenylyl cyclase activity; opening of calcium channel. (cardiac stimulants; used to treat cardiogenic shock, acute heart failure, bradyarrhythmias). Selected examples are:- DobutamineDobutamineDobutamine is a sympathomimetic drug used in the treatment of heart failure and cardiogenic shock. Its primary mechanism is direct stimulation of β1 receptors of the sympathetic nervous system. Dobutamine was developed by a laboratory led by Drs...
- IsoproterenolIsoproterenolIsoprenaline or isoproterenol is a medication used for the treatment of bradycardia , heart block, and rarely for asthma...
(β1 and β2) - XamoterolXamoterolXamoterol is a cardiac stimulant. It works by binding to the β1 adrenergic receptor. it is a 3rd generation andrenergics beta receptor partial agonist. it provides cardiac stimulation when patient is at rest but it acts as a blocker during exercise....
- epinephrineEpinephrineEpinephrine is a hormone and a neurotransmitter. It increases heart rate, constricts blood vessels, dilates air passages and participates in the fight-or-flight response of the sympathetic nervous system. In chemical terms, adrenaline is one of a group of monoamines called the catecholamines...
β2 agonists
β2 agonists: stimulates adenylyl cyclase activity; closing of calcium channel (smooth muscle relaxants; used to treat asthma and COPD). Selected examples are:- salbutamolSalbutamolSalbutamol or albuterol is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease. It is marketed as Ventolin among other brand names....
(albuterol in USA) - FenoterolFenoterolFenoterol is an asthma medication designed to open up the airways to the lungs. It is classed as sympathomimetic beta2 agonist.Fenoterol is produced and sold by Boehringer Ingelheim as Berotec N and in combination with ipratropium as Berodual N....
- FormoterolFormoterolFormoterol or eformoterol is a long-acting β2-agonist used in the management of asthma and/or chronic obstructive pulmonary disease...
- IsoproterenolIsoproterenolIsoprenaline or isoproterenol is a medication used for the treatment of bradycardia , heart block, and rarely for asthma...
(β1 and β2) - Metaproterenol
- SalmeterolSalmeterolSalmeterol is a long-acting beta2-adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease. It is currently available as a dry powder inhaler that releases a powdered form of the drug...
- TerbutalineTerbutalineTerbutaline is a β2-adrenergic receptor agonist.Terbutaline is currently on the World Anti-Doping Agency's list of prohibited drugs for Olympic athletes, except when administered by inhalation and a Therapeutic Use Exemption has been obtained in advance.Terbutaline is currently used to delay...
- ClenbuterolClenbuterolClenbuterol is a sympathomimetic amine used by sufferers of breathing disorders as a decongestant and bronchodilator. People with chronic breathing disorders such as asthma use this as a bronchodilator to make breathing easier...
- IsoetarineIsoetarineIsoetarine or isoetharine , trade names Bronkosol and Bronkometer, is a selective beta2-adrenergic receptor agonist. It can be called the "granddaughter of adrenalin" in the line of beta-two antagonists that gave quick relief for brochospasm and asthma. Adrenalin or epinephrine was the first of...
- pirbuterolPirbuterolPirbuterol is a beta-2 adrenergic bronchodilator used in the treatment of asthma, available as a breath-activated metered-dose inhaler .-Clinical use:...
- procaterolProcaterolProcaterol, applied as procaterol hydrochloride , is a short-acting β2-adrenergic receptor agonist used for the treatment of asthma. It has never been filed for FDA evaluation in the United States, where it is not marketed. The drug is readily oxidated in the presence of moisture and air, making it...
- ritodrineRitodrineRitodrine is a tocolytic drug, was used to stop premature labor. It is available in oral tablets or as an injection, and is typically used as the hydrochloride salt, ritodrine hydrochloride...
- epinephrineEpinephrineEpinephrine is a hormone and a neurotransmitter. It increases heart rate, constricts blood vessels, dilates air passages and participates in the fight-or-flight response of the sympathetic nervous system. In chemical terms, adrenaline is one of a group of monoamines called the catecholamines...
Undetermined/unsorted
The following agents are also listed as agonists by MeSHMedical Subject Headings
Medical Subject Headings is a comprehensive controlled vocabulary for the purpose of indexing journal articles and books in the life sciences; it can also serve as a thesaurus that facilitates searching...
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- arbutamineArbutamineArbutamine is a cardiac stimulant.It stimulates adrenergic receptors.-References:...
- befunololBefunololBefunolol is a beta blocker with intrinsic sympathomimetic activity used in the management of open-angle glaucoma....
- bromoacetylalprenololmenthaneBromoacetylalprenololmenthaneBromoacetylalprenololmenthane is a beta-adrenergic agonist....
- broxaterolBroxaterolBroxaterol is a beta-adrenergic agonist....
- cimaterolCimaterolCimaterol is a beta-adrenergic agonist....
- cirazolineCirazolineCirazoline is a nonselective agonist of the alpha-1 adrenergic receptor , and an antagonist to the alpha-2 adrenergic receptor. It is believed that this combination of properties could make cirazoline an effective vasoconstricting agent....
- denopamineDenopamineDenopamine is a cardiotonic drug which acts as a Beta-1 adrenergic receptor agonist. It is used in the treatment of angina and may also have potential uses in the treatment of congestive heart failure and for clearing pulmonary oedema....
- dopexamineDopexamineDopexamine is a β2-adrenergic receptor agonist. It also acts at dopamine receptors.Use in sepsis has been proposed.It is considered a inotropic agent....
- etilefrineEtilefrineEtilefrine is a cardiac stimulant used as an antihypotensive. It is a sympathomimetic amine of the 3-hydroxy-phenylethanolamine series used in treating orthostatic hypotension of neurological, cardiovascular, endocrine or metabolic origin...
- hexoprenalineHexoprenalineHexoprenaline is a β2-adrenergic receptor agonist used in the treatment of asthma.Hexoprenaline is also used as a tocolytic agent . Contraindications to its use as a tocolytic agent are cardiovascular disease, surgical shock, tachycardia, diabetes mellitus....
- higenamineHigenamineHigenamine is a beta-adrenergic agonist. Higenamine is also known as norcoclaurine.-norcoclaurine is a precursor in plant benzylisoquinoline alkaloid synthesis. The formation of -norcoclaurine is catalyzed by -norcoclaurine synthase....
- isoxsuprineIsoxsuprineIsoxsuprine, or Isoxsuprine hydrochloride, is a drug used as a vasodilator in humans and equines.-Reasons for use and controversy:Isoxsuprine is most commonly used to treat hoof-related problems in the horse, most commonly for laminitis and navicular disease, as its effects as a vasodilator are...
- mabuterolMabuterolMabuterol is a beta-adrenergic agonist....
- methoxyphenamineMethoxyphenamineMethoxyphenamine , also known as 2-methoxy-N-methylamphetamine , is a β-adrenergic receptor agonist of the amphetamine class used as a bronchodilator....
- nylidrin
- oxyfedrineOxyfedrineOxyfedrine is a vasodilator.Synergestic effects with antibiotics have been suggested....
- prenalterolPrenalterolPrenalterol is a cardiac stimulant which acts as a β1-adrenergic agonist.- References :...
- ractopamineRactopamineRactopamine is a drug that is used as a feed additive to promote leanness in pigs raised for their meat. Pharmacologically, it is a beta-adrenoceptor agonist. It is the active ingredient in products known as Paylean for swine and Optaflexx for cattle, developed by Elanco Animal Health, a division...
- reproterolReproterolReproterol is a β2-adrenergic receptor agonist used in the treatment of asthma....
- rimiterolRimiterolRimiterol is a third-generation β2-agonist....
- tretoquinolTretoquinolTretoquinol is a beta-adrenergic agonist.- Notes and references :Tretoquinol is a beta-adrenergic agonist.- Notes and references :Tretoquinol is a beta-adrenergic agonist....
- tulobuterolTulobuterolTulobuterol is a long-acting beta2-adrenergic receptor agonist, marketed in Japan as a transdermal patch under the name Hokunalin tape ....
- zilpaterolZilpaterolZilpaterol is a beta-adrenergic agonist....
- zinterolZinterolZinterol is a beta-adrenergic agonist....