Beta-actin
Encyclopedia
Beta-actin is one of six different actin
Actin
Actin is a globular, roughly 42-kDa moonlighting protein found in all eukaryotic cells where it may be present at concentrations of over 100 μM. It is also one of the most highly-conserved proteins, differing by no more than 20% in species as diverse as algae and humans...

 isoforms which have been identified in humans. This is one of the two nonmuscle cytoskeletal actins. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus.

Beta actin is usually used as a loading control, for among others, the integrity of cells, protein degradation, in Western Blotting.

Interactions

Beta-actin has been shown to interact
Protein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...

 with SPTBN2
SPTBN2
Spectrin beta chain, brain 2 is a protein that in humans is encoded by the SPTBN2 gene.-Interactions:SPTBN2 has been shown to interact with UNC13B, ACTR1A and Beta-actin.-Further reading:...

.

Further reading

See also

  • Actin
    Actin
    Actin is a globular, roughly 42-kDa moonlighting protein found in all eukaryotic cells where it may be present at concentrations of over 100 μM. It is also one of the most highly-conserved proteins, differing by no more than 20% in species as diverse as algae and humans...

  • ACTA1
    ACTA1
    Actin, alpha skeletal muscle is a protein that in humans is encoded by the ACTA1 gene.-Skeletal actin gene expression:Skeletal alpha actin expression is induced by stimuli and conditions known to cause muscle formation. Such conditions result in fusion of committed cells into myotubes, to form...

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