Beta-Bungarotoxin
Encyclopedia
β-Bungarotoxin is a form of bungarotoxin
that is fairly common in Krait venoms.
The target of this neurotoxin is at the presynaptic terminal, where it causes release of acetylcholine
and subsequent exhaustion of acetylcholine stores in the nerve terminal, by binding to proteins, most commonly actin
. There are two isoforms, β1-bungarotoxin and β2-bungarotoxin.
It consists of two chains.
Bungarotoxin
α-Bungarotoxin is one of the components of the venom of the elapid snake Taiwanese banded krait . It binds irreversibly and competitively to the acetylcholine receptor found at the neuromuscular junction, causing paralysis, respiratory failure and death in the victim...
that is fairly common in Krait venoms.
The target of this neurotoxin is at the presynaptic terminal, where it causes release of acetylcholine
Acetylcholine
The chemical compound acetylcholine is a neurotransmitter in both the peripheral nervous system and central nervous system in many organisms including humans...
and subsequent exhaustion of acetylcholine stores in the nerve terminal, by binding to proteins, most commonly actin
Actin
Actin is a globular, roughly 42-kDa moonlighting protein found in all eukaryotic cells where it may be present at concentrations of over 100 μM. It is also one of the most highly-conserved proteins, differing by no more than 20% in species as diverse as algae and humans...
. There are two isoforms, β1-bungarotoxin and β2-bungarotoxin.
It consists of two chains.