Band cell
Encyclopedia
Granulopoiesis
Granulopoiesis is hematopoiesis of granulocytes.It occurs primarily within bone marrow and involves the following stages:* Pluripotential hemopoietic stem cell* Myeloblast* Promyelocyte* Eosino/neutro/basophilic myelocyte...
, derived from a metamyelocyte
Metamyelocyte
A metamyelocyte is a cell undergoing granulopoiesis, derived from a myelocyte, and leading to a band cell.It is characterized by the appearance of a bent nucleus, cytoplasmic granules, and the absence of visible nucleoli...
, and leading to a mature granulocyte
Granulocyte
Granulocytes are a category of white blood cells characterized by the presence of granules in their cytoplasm. They are also called polymorphonuclear leukocytes because of the varying shapes of the nucleus, which is usually lobed into three segments...
.
It is characterized by having a nucleus
Cell nucleus
In cell biology, the nucleus is a membrane-enclosed organelle found in eukaryotic cells. It contains most of the cell's genetic material, organized as multiple long linear DNA molecules in complex with a large variety of proteins, such as histones, to form chromosomes. The genes within these...
which is curved, but not lobar.
Often the term "band cell" implies a neutrophilic lineage. However, the term is not used only with neutrophils.
A count of band neutrophils is used to measure inflammation
Inflammation
Inflammation is part of the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. Inflammation is a protective attempt by the organism to remove the injurious stimuli and to initiate the healing process...
. An excess is called bandemia
Bandemia
Bandemia refers to an excess of band cells released by the bone marrow into the blood. The ICD diagnosis code for bandemia is 288.66.It is a signifier of infection or inflammation....
.
